Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling. (Q37246666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351789%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling (English)

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25 January 2020

3

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25 January 2020

author name string

Junichi Inokuchi

series ordinal

1

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25 January 2020

Alice Lau

series ordinal

2

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25 January 2020

David K Ornstein

series ordinal

4

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25 January 2020

language of work or name

English

0 references

publication date

7 April 2009

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25 January 2020

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25 January 2020

volume

30

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25 January 2020

issue

7

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25 January 2020

page(s)

1082-1088

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STAT3 can be activated through paracrine signaling in breast epithelial cells

25 January 2020

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1 reference

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Autocrine IL-6 signaling: a key event in tumorigenesis?

6 September 2017

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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

6 September 2017

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Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

6 September 2017

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The NF-kappaB/IL-6 pathway in metastatic androgen-independent prostate cancer: new therapeutic approaches?

6 September 2017

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6 September 2017

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6 September 2017

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Lack of annexin 1 results in an increase in corticotroph number in male but not female mice

6 September 2017

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6 September 2017

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6 September 2017

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The role of IL-6 and STAT3 in inflammation and cancer

6 September 2017

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Annexins: linking Ca2+ signalling to membrane dynamics

6 September 2017

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Interleukin-6 regulation of prostate cancer cell growth

6 September 2017

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6 September 2017

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Interleukin-6: from basic science to medicine--40 years in immunology

6 September 2017

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

6 September 2017

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The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis

6 September 2017

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Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

6 September 2017

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Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1

6 September 2017

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BCL-2 in prostate cancer: a minireview

6 September 2017

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Dysregulation of the annexin family protein family is associated with prostate cancer progression

6 September 2017

1 reference

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Phospholipase A(2) regulation of arachidonic acid mobilization

6 September 2017

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Annexins: from structure to function

6 September 2017

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Interleukin-6 is an autocrine growth factor in human prostate cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma

6 September 2017

1 reference

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Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma

6 September 2017

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Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers

6 September 2017

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Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity

6 September 2017

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Expression of annexin I, II and VII proteins in androgen stimulated and recurrent prostate cancer

6 September 2017

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Dysregulation of annexin I protein expression in high-grade prostatic intraepithelial neoplasia and prostate cancer.

14 September 2017

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Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells.

14 September 2017

1 reference

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14 September 2017

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Annexin 1 negatively regulates IL-6 expression via effects on p38 MAPK and MAPK phosphatase-1.

14 September 2017

1 reference

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Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.

14 September 2017

1 reference

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The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells.

14 September 2017

1 reference

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Prostaglandin E(2) stimulates prostatic intraepithelial neoplasia cell growth through activation of the interleukin-6/GP130/STAT-3 signaling pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Interleukin-6 in biology and medicine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

Mcl-1 is regulated by IL-6 and mediates the survival activity of the cytokine in a model of late stage prostate carcinoma

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704280

The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.

3 September 2018

1 reference

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

3 September 2018

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Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer

3 September 2018

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12 December 2020

IL-6 signaling promotes tumor growth in colorectal cancer

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12 December 2020

Decreased annexin I expression in prostatic adenocarcinoma and in high-grade prostatic intraepithelial neoplasia

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12 December 2020

Differential effects of annexins I, II, III, and V on cytosolic phospholipase A2 activity: specific interaction model

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12 December 2020

Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro

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12 December 2020

Characterization of the role of IL-6 in the progression of prostate cancer

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12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGP078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351789%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19351789%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

19351789

1 reference