Interstitial leukocyte migration and immune function (Q37246683)

19 August 2017

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title

Interstitial leukocyte migration and immune function (English)

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19 August 2017

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Peter Friedl

1

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PubMed ID

18711433

19 August 2017

Bettina Weigelin

series ordinal

2

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PubMed ID

18711433

19 August 2017

language of work or name

English

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publication date

1 September 2008

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19 August 2017

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19 August 2017

9

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19 August 2017

960-969

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19 August 2017

9

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T-Cell Function and Migration — Two Sides of the Same Coin

19 August 2017

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7 January 2021

T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node

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7 January 2021

Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes

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7 January 2021

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

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7 January 2021

Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment

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7 January 2021

Getting to the site of inflammation: the leukocyte adhesion cascade updated

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7 January 2021

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

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7 January 2021

Moving targets: cell migration inhibitors as new anti-inflammatory therapies

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7 January 2021

Prespecification and plasticity: shifting mechanisms of cell migration

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7 January 2021

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

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7 January 2021

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

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7 January 2021

Collective cell migration in morphogenesis and cancer

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7 January 2021

TCR triggering on the move: diversity of T-cell interactions with antigen-presenting cells

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7 January 2021

Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling

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7 January 2021

Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell

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7 January 2021

Polarity of T cell shape, motility, and sensitivity to antigen

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7 January 2021

A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis

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7 January 2021

Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils

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7 January 2021

Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis

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7 January 2021

Topographic distribution of CD18 integrin on human neutrophils as related to shape changes and movement induced by chemotactic peptide and phorbol esters

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7 January 2021

CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion.

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7 January 2021

Entactin stimulates neutrophil adhesion and chemotaxis through interactions between its Arg-Gly-Asp (RGD) domain and the leukocyte response integrin

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7 January 2021

A site on laminin alpha 5, AQARSAASKVKVSMKF, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis.

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7 January 2021

How chemokines invite leukocytes to dance

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7 January 2021

Targeting phosphoinositide 3-kinase: moving towards therapy

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7 January 2021

Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration

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7 January 2021

Akt/PKB regulates actin organization and cell motility via Girdin/APE

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7 January 2021

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

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7 January 2021

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

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7 January 2021

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7 January 2021

Feedback signaling controls leading-edge formation during chemotaxis

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7 January 2021

A quantitative analysis of contractility in active cytoskeletal protein networks.

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7 January 2021

Microtubule asymmetry during neutrophil polarization and migration.

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7 January 2021

Rapid leukocyte migration by integrin-independent flowing and squeezing

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7 January 2021

PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis

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7 January 2021

Regulation of PTEN by Rho small GTPases

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7 January 2021

Orchestration of lymphocyte chemotaxis by mitochondrial dynamics

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7 January 2021

T cell migration in three-dimensional extracellular matrix: guidance by polarity and sensations

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7 January 2021

Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix

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7 January 2021

Mapping proteolytic cancer cell-extracellular matrix interfaces

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7 January 2021

Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils

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7 January 2021

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

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7 January 2021

Clipping, shedding and RIPping keep immunity on cue.

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7 January 2021

Proteolytic and non-proteolytic migration of tumour cells and leucocytes

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7 January 2021

Lymphoma dissemination: the other face of lymphocyte homing

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7 January 2021

Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulate alpha v integrin expression on cultured human macrophages

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7 January 2021

Beta1 and beta2 integrins mediate adhesion during macrophage fusion and multinucleated foreign body giant cell formation

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7 January 2021

Macrophage matrix metalloproteinase-2/-9 gene and protein expression following adhesion to ECM-derived multifunctional matrices via integrin complexation

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7 January 2021

Orchestrating the orchestrators: chemokines in control of T cell traffic

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7 January 2021

PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane

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7 January 2021

Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice

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7 January 2021

Inhibition of MMP-dependent chemotaxis and amelioration of experimental autoimmune uveitis with a selective metalloproteinase-2 and -9 inhibitor.

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7 January 2021

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

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7 January 2021

Human neutrophils do not degrade major basement membrane components during chemotactic migration

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7 January 2021

Leukocyte diapedesis and plasma extravasation after leukotriene B4: lack of structural injury to the endothelium

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7 January 2021

Transendothelial migration induces rapid expression on neutrophils of granule-release VLA6 used for tissue infiltration

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7 January 2021

Functional consequences of noncognate interactions between CD4+ memory T lymphocytes and the endothelium

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7 January 2021

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

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7 January 2021

Visualizing dendritic cell networks in vivo

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7 January 2021

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

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7 January 2021

A chemokine-driven positive feedback loop organizes lymphoid follicles

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7 January 2021

In vivo imaging of leukocyte trafficking in blood vessels and tissues

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7 January 2021

Surface-bound chemokines capture and prime T cells for synapse formation

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7 January 2021

Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

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7 January 2021

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

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7 January 2021

A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo

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7 January 2021

Tuning immune responses: diversity and adaptation of the immunological synapse.

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7 January 2021

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

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7 January 2021

Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node

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7 January 2021

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

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7 January 2021

Integrin-mediated long-term B cell retention in the splenic marginal zone.

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7 January 2021

T cells use two directionally distinct pathways for cytokine secretion.

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7 January 2021

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

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7 January 2021

Cognate CD4+ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes

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7 January 2021

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

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7 January 2021

Dendritic epidermal T cells (DETC) are diminished in integrin alphaE(CD103)-deficient mice

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7 January 2021

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin

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7 January 2021

Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

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7 January 2021

Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.

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7 January 2021

Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential

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7 January 2021

Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs

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7 January 2021

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress

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7 January 2021

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.

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7 January 2021

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

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7 January 2021

Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation

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7 January 2021

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

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7 January 2021

A close-up view of migrating Langerhans cells in the skin.

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7 January 2021

Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone.

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7 January 2021

Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

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7 January 2021

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics

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7 January 2021

Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

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7 January 2021

Macrophage mannose receptor on lymphatics controls cell trafficking

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7 January 2021

CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium

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7 January 2021

Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

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7 January 2021

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

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7 January 2021

Lymphoid neogenesis in chronic inflammatory diseases.

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7 January 2021

Chronic inflammation caused by lymphotoxin is lymphoid neogenesis

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7 January 2021

Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis

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7 January 2021

Evolving concepts of rheumatoid arthritis

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7 January 2021

Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

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7 January 2021

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

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7 January 2021

Role of leukotriene B4 receptors in rheumatoid arthritis

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7 January 2021

In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor

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7 January 2021

Two-photon imaging of intratumoral CD8+ T cell cytotoxic activity during adoptive T cell therapy in mice

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7 January 2021

Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment

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7 January 2021

Tumor-associated fibroblasts recruit blood monocytes into tumor tissue.

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7 January 2021

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

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7 January 2021

CXC chemokine ligand 12 (stromal cell-derived factor 1 alpha) and CXCR4-dependent migration of CTLs toward melanoma cells in organotypic culture

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7 January 2021

CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis

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7 January 2021

Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells.

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7 January 2021

Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines

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7 January 2021

Random migration precedes stable target cell interactions of tumor-infiltrating T cells.

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7 January 2021

Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion.

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7 January 2021

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

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7 January 2021

Regulation of T cell migration during viral infection: role of adhesion molecules and chemokines

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7 January 2021

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

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7 January 2021

Adhesion of lymphocytes to hepatic endothelium

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7 January 2021

T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells

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7 January 2021

Trafficking of recirculating lymphocytes in the rat liver: rapid transmigration into the portal area and then to the hepatic lymph.

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7 January 2021

Life, activation and death of intrahepatic lymphocytes in chronic hepatitis C.

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7 January 2021

CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection

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7 January 2021

Life and death in the granuloma: immunopathology of tuberculosis

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7 January 2021

Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

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7 January 2021

Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis

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7 January 2021

Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice

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7 January 2021

FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors

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7 January 2021

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

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7 January 2021

Enhanced type I interferon signaling and recruitment of chemokine receptor CXCR3-expressing lymphocytes into the skin following treatment with the TLR7-agonist imiquimod.

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7 January 2021

TLR7 and TLR8 as targets in cancer therapy

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7 January 2021

RhoA is involved in LFA-1 extension triggered by CXCL12 but not in a novel outside-in LFA-1 activation facilitated by CXCL9.

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7 January 2021

Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody

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7 January 2021

Identifiers

DOI

10.1038/NI.F.212

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19 August 2017

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PubMed ID

18711433