Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance (Q37249150)

19 August 2017

Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance (English)

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19 August 2017

John W Thompson

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19 August 2017

Kunjan R Dave

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2

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19 August 2017

Juan I Young

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3

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19 August 2017

Miguel A Perez-Pinzon

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4

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19 August 2017

1 October 2013

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19 August 2017

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19 August 2017

10

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19 August 2017

4

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19 August 2017

789-797

1 reference

https://scigraph.springernature.com/pub.10.1007/s13311-013-0202-9

19 August 2017

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SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain

6 September 2017

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Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein

6 September 2017

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SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression

6 September 2017

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Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death

6 September 2017

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6 September 2017

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6 September 2017

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Can genes modify stroke outcome and by what mechanisms?

6 September 2017

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Stroke research at a crossroad: asking the brain for directions

6 September 2017

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SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Protective effects and mechanisms of sirtuins in the nervous system

6 September 2017

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SIRT1-mediated acute cardioprotection

6 September 2017

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Chromatin higher-order structures and gene regulation

6 September 2017

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Regulation of chromatin by histone modifications

6 September 2017

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Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning

6 September 2017

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Emerging role of epigenetics in stroke: part 1: DNA methylation and chromatin modifications

6 September 2017

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Signal transducers and activators of transcription: STATs-mediated mitochondrial neuroprotection

6 September 2017

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Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury

6 September 2017

1 reference

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miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia

6 September 2017

1 reference

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Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex

6 September 2017

1 reference

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Genomic analysis of ischemic preconditioning in adult rat hippocampal slice cultures.

6 September 2017

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Protein kinase C epsilon activation delays neuronal depolarization during cardiac arrest in the euthermic arctic ground squirrel

6 September 2017

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Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

SUMOylation participates in induction of ischemic tolerance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

RNA regulation of epigenetic processes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection

6 September 2017

1 reference

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SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

6 September 2017

1 reference

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Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Phenotypic plasticity and the epigenetics of human disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

1,026 experimental treatments in acute stroke

6 September 2017

1 reference

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6 September 2017

1 reference

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Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Translating the Histone Code

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Ischemic pre-conditioning alters cerebral microRNAs that are upstream to neuroprotective signaling pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

DNA methyltransferase contributes to delayed ischemic brain injury.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Cortical spreading depression differentially affects lysine methylation of H3 histone at neuroprotective genes and retrotransposon sequences.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Expression patterns of histone deacetylases in experimental stroke and potential targets for neuroprotection.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Gene expression analysis to identify molecular correlates of pre- and post-conditioning derived neuroprotection.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

The arctic ground squirrel brain is resistant to injury from cardiac arrest during euthermia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Resveratrol mimics ischemic preconditioning in the brain

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

Preconditioning provides complete protection against retinal ischemic injury in rats.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805868

SUMO engages multiple corepressors to regulate chromatin structure and transcription

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23868468

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13311-013-0202-9

1 reference

release_cyt3nnynjbgzthwyjn5l3uqngy

19 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cyt3nnynjbgzthwyjn5l3uqngy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

19 August 2017

1 reference