Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels (Q37250548)

19 August 2017

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels (English)

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19 August 2017

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13

Moungi G Bawendi

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Triantafyllos Stylianopoulos

19 August 2017

7

object named as

Triantafyllos Stylianopoulos

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19 August 2017

15

Rakesh K Jain

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19 August 2017

5

Saloni R Jain

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19 August 2017

9

Xiaoxing Han

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19 August 2017

12

Peigen Huang

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19 August 2017

1

Vikash P Chauhan

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19 August 2017

4

Delphine A Lacorre

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19 August 2017

John D Martin

2

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19 August 2017

Hao Liu

3

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19 August 2017

Sergey V Kozin

6

1 reference

19 August 2017

Ahmed S Mousa

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19 August 2017

Pichet Adstamongkonkul

10

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19 August 2017

Zoran Popović

11

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19 August 2017

Yves Boucher

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19 August 2017

language of work or name

English

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publication date

1 January 2013

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19 August 2017

Nature Communications

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19 August 2017

4

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19 August 2017

2516

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

19 August 2017

start time

1 October 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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6 September 2017

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Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse

6 September 2017

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A systematic comparison of the properties of clinically used angiotensin II type 1 receptor antagonists

6 September 2017

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TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.

6 September 2017

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Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

6 September 2017

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Angiotensin II facilitates breast cancer cell migration and metastasis

6 September 2017

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Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

6 September 2017

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

6 September 2017

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Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies.

6 September 2017

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Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation

6 September 2017

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Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

6 September 2017

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Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion.

6 September 2017

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Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration

6 September 2017

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Impaired lymphatic contraction associated with immunosuppression

6 September 2017

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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

6 September 2017

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Angiotensin system inhibitors and outcome of sunitinib treatment in patients with metastatic renal cell carcinoma: a retrospective examination

6 September 2017

1 reference

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Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

6 September 2017

1 reference

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Scaling rules for diffusive drug delivery in tumor and normal tissues

6 September 2017

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Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine

6 September 2017

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The renin-angiotensin system and cancer: old dog, new tricks.

6 September 2017

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Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist

6 September 2017

1 reference

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Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis

6 September 2017

1 reference

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Perfusion CT: noninvasive surrogate marker for stratification of pancreatic cancer response to concurrent chemo- and radiation therapy.

6 September 2017

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Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma

6 September 2017

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Cell mechanics: integrating cell responses to mechanical stimuli

6 September 2017

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Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors

6 September 2017

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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

6 September 2017

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Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

6 September 2017

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Effects of angiotensin II receptor antagonist, Losartan on the apoptosis, proliferation and migration of the human pancreatic stellate cells

6 September 2017

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Pathology: cancer cells compress intratumour vessels.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

The angiotensin-I-converting enzyme inhibitor perindopril suppresses tumor growth and angiogenesis: possible role of the vascular endothelial growth factor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II type 1A receptor signaling facilitates tumor metastasis formation through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II stimulates DNA synthesis of rat pancreatic stellate cells by activating ERK through EGF receptor transactivation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Angiotensin II activates extracellular signal regulated kinases via protein kinase C and epidermal growth factor receptor in breast cancer cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Universal GFP reporter for the study of vascular development.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3806395

In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy

3 December 2018

1 reference

12 December 2020

Oxygen gradients in the microcirculation

1 reference

12 December 2020

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β1

1 reference

12 December 2020

Angiotensin II Type 1a Receptor-deficient Mice with Hypotension and Hyperreninemia

1 reference

12 December 2020

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

12 December 2020

Solid stress inhibits the growth of multicellular tumor spheroids

1 reference

12 December 2020

Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP

1 reference

12 December 2020

Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis

1 reference

12 December 2020

Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy

1 reference

12 December 2020

Reduced risk of breast cancer recurrence in patients using ACE inhibitors, ARBs, and/or statins

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS3516

1 reference

Dimensions Publication ID

19 August 2017

0 references

0 references

1 reference

19 August 2017

PubMed publication ID

24084631

1 reference