A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model (Q37259695)

19 August 2017

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model (English)

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19 August 2017

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Tara L Spires-Jones

2

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Bradley Hyman

series ordinal

4

object named as

Bradley T Hyman

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19 August 2017

1

Anete Rozkalne

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19 August 2017

Edward A Stern

3

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PMCID

2709805

19 August 2017

language of work or name

English

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publication date

22 May 2009

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19 August 2017

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19 August 2017

1280

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19 August 2017

178-185

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PMCID

2709805

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2709805/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

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Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

6 September 2017

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

6 September 2017

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

6 September 2017

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Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model

6 September 2017

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Neuronal structure is altered by amyloid plaques

6 September 2017

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Imaging amyloid-beta deposits in vivo

6 September 2017

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Reversible memory loss in a mouse transgenic model of Alzheimer's disease

6 September 2017

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

6 September 2017

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

6 September 2017

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Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

6 September 2017

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

6 September 2017

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

6 September 2017

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

6 September 2017

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Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice

6 September 2017

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Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

28 September 2017

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

26 June 2018

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Neuritic pathology and dementia in Alzheimer's disease.

26 June 2018

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Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

26 June 2018

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Plaque-derived oxidative stress mediates distorted neurite trajectories in the Alzheimer mouse model.

3 September 2018

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Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

3 September 2018

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In vivo imaging of amyloid-beta deposits in mouse brain with multiphoton microscopy

3 September 2018

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Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

3 September 2018

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Dendrite and dendritic spine alterations in Alzheimer models

3 September 2018

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

3 September 2018

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Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques.

3 September 2018

1 reference

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Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

3 September 2018

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Amyloid-beta antibody treatment leads to rapid normalization of plaque-induced neuritic alterations.

3 September 2018

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In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories

3 September 2018

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Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative

3 September 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

3 September 2018

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Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption

3 September 2018

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Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709805

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

3 September 2018

1 reference

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Visual memory predicts Alzheimer's disease more than a decade before diagnosis

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19465012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Abeta associated neuropil changes: correlation with neuronal loss and dementia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19465012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BRAINRES.2009.05.045

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

2709805