AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR. (Q37264143)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19419994%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR (English)

1 reference

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27 January 2020

0 references

6

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27 January 2020

author name string

J Darwin King

1

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27 January 2020

Adam C Fitch

2

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27 January 2020

Jeffrey K Lee

3

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27 January 2020

Jill E McCane

4

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27 January 2020

Don-On Daniel Mak

5

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27 January 2020

Kenneth R Hallows

7

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27 January 2020

publication date

6 May 2009

1 reference

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American Journal of Physiology - Cell Physiology

27 January 2020

published in

1 reference

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27 January 2020

volume

297

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27 January 2020

issue

1

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27 January 2020

page(s)

C94-101

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AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells

27 January 2020

cites work

1 reference

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Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells

6 September 2017

1 reference

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Emerging role of AMP-activated protein kinase in coupling membrane transport to cellular metabolism

6 September 2017

1 reference

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Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

6 September 2017

1 reference

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Management of cellular energy by the AMP-activated protein kinase system

6 September 2017

1 reference

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Regulation of channel gating by AMP-activated protein kinase modulates cystic fibrosis transmembrane conductance regulator activity in lung submucosal cells

6 September 2017

1 reference

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Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factor

6 September 2017

1 reference

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AMP-activated protein kinase: the energy charge hypothesis revisited

6 September 2017

1 reference

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An activating mutation in the gamma1 subunit of the AMP-activated protein kinase

6 September 2017

1 reference

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Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase

6 September 2017

1 reference

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Identification of the cystic fibrosis gene: chromosome walking and jumping

6 September 2017

1 reference

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

6 September 2017

1 reference

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Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP.

6 September 2017

1 reference

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AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.

14 September 2017

1 reference

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Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

14 September 2017

1 reference

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PKA holoenzyme is functionally coupled to CFTR by AKAPs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Cystic fibrosis: How do CFTR mutations cause cystic fibrosis?

28 September 2017

1 reference

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The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.

28 September 2017

1 reference

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Mechanistic insight into control of CFTR by AMPK.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Phosphorylation by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Dibasic phosphorylation sites in the R domain of CFTR have stimulatory and inhibitory effects on channel activation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Stimulation of CFTR activity by its phosphorylated R domain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2711654

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19419994

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPCELL.00677.2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19419994%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19419994%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference