Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord (Q37265996)

19 August 2017

Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord (English)

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19 August 2017

8

Zena Werb

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author name string

Jung-Yu C Hsu

1

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19 August 2017

Lilly Y W Bourguignon

2

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19 August 2017

Christen M Adams

3

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19 August 2017

Karine Peyrollier

4

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19 August 2017

Haoqian Zhang

5

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19 August 2017

Thomas Fandel

6

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19 August 2017

Christine L Cun

7

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19 August 2017

Zena Werb

8

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19 August 2017

Linda J Noble-Haeusslein

9

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19 August 2017

language of work or name

English

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publication date

1 December 2008

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19 August 2017

Journal of Neuroscience

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19 August 2017

28

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19 August 2017

50

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19 August 2017

13467-13477

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describes a project that uses

19 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2712293/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

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The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury

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Chondroitinase ABC promotes functional recovery after spinal cord injury

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6 September 2017

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Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion

6 September 2017

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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

6 September 2017

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6 September 2017

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Bradykinin induces matrix metalloproteinase-9 expression and cell migration through a PKC-delta-dependent ERK/Elk-1 pathway in astrocytes

6 September 2017

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Genes associated with adult axon regeneration promoted by olfactory ensheathing cells: a new role for matrix metalloproteinase 2.

14 September 2017

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14 September 2017

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Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes.

14 September 2017

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Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.

14 September 2017

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CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells

14 September 2017

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Reactive astrocytes: cellular and molecular cues to biological function

28 September 2017

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Expression and effects of hyaluronan and of the hyaluronan-binding protein hyaluronectin in newborn rat brain glial cell cultures

26 June 2018

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Expression of fibronectin and laminin by different types of mouse glial cells cultured in a serum-free medium

26 June 2018

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Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes.

26 June 2018

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Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

3 September 2018

1 reference

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Involvement of aquaporin-4 in astroglial cell migration and glial scar formation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing.

3 September 2018

1 reference

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P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration

3 September 2018

1 reference

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An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

3 September 2018

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MMP-9 deficiency affects axonal outgrowth, migration, and apoptosis in the developing cerebellum.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury.

3 September 2018

1 reference

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Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Requirement of functional ryanodine receptor type 3 for astrocyte migration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Regulation of astrocyte morphology by RhoA and lysophosphatidic acid.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Osteopontin and its integrin receptor alpha(v)beta3 are upregulated during formation of the glial scar after focal stroke

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712293

The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar

3 September 2018

1 reference

12 December 2020

Neurocan is upregulated in injured brain and in cytokine-treated astrocytes

1 reference

12 December 2020

1 reference

12 December 2020

NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.

1 reference

12 December 2020

Chondroitinase ABC enhances axonal regrowth through Schwann cell-seeded guidance channels after spinal cord injury

1 reference

12 December 2020

Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan

1 reference

12 December 2020

MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity

1 reference

12 December 2020

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1 reference

12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

1 reference

12 December 2020

10.1523/JNEUROSCI.2287-08.2008

Identifiers

DOI

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

19074020

1 reference