Ionizing radiation activates transcription of the EGR1 gene via CArG elements (Q37268671)

19 August 2017

Ionizing radiation activates transcription of the EGR1 gene via CArG elements (English)

1 reference

19 August 2017

immediate-early proteins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332031

14 September 2022

promoter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332031

14 September 2022

author name string

R. Datta

1

1 reference

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14 September 2022

E. Rubin

2

1 reference

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14 September 2022

V. Sukhatme

3

1 reference

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14 September 2022

S. Qureshi

4

1 reference

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14 September 2022

D. Hallahan

5

1 reference

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14 September 2022

R. R. Weichselbaum

6

1 reference

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14 September 2022

D. W. Kufe

7

1 reference

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14 September 2022

language of work or name

English

0 references

publication date

1 November 1992

1 reference

PMC publication ID

50295

full work available at URL

19 August 2017

https://europepmc.org/articles/PMC50295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332031

https://europepmc.org/articles/PMC50295?pdf=render

14 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1332031

Proceedings of the National Academy of Sciences of the United States of America

14 September 2022

published in

1 reference

19 August 2017

89

1 reference

19 August 2017

21

1 reference

19 August 2017

10149-10153

1 reference

Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

6 September 2017

1 reference

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Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc

6 September 2017

1 reference

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Translocation of protein kinase C in human leukemia cells susceptible or resistant to differentiation induced by phorbol 12-myristate 13-acetate

6 September 2017

1 reference

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Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant

6 September 2017

1 reference

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A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences

6 September 2017

1 reference

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Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Functional serum response elements upstream of the growth factor-inducible gene zif268

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

DNA binding site of the growth factor-inducible protein Zif268

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

The SRE: a growth factor responsive transcriptional regulator

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Ionizing radiation regulates expression of the c-jun protooncogene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Insertion of synthetic copies of human globin genes into bacterial plasmids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Two distinct cellular phosphoproteins bind to the c-fos serum response element

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Effects of irradiation on the release of growth factors from cultured bovine, porcine, and human endothelial cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Posttranscriptional regulation of the zinc finger-encoding EGR-1 gene by granulocyte-macrophage colony-stimulating factor in human U-937 monocytic leukemia cells: involvement of a pertussis toxin-sensitive G protein

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Distinct protein targets for signals acting at the c-fos serum response element

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50295

Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element

26 June 2018

1 reference

12 December 2020

Inducible binding of a factor to the c-fos enhancer

1 reference

12 December 2020

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens

1 reference

12 December 2020

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1 reference

12 December 2020

Identification of c-fos sequences involved in induction by insulin and phorbol esters

1 reference

12 December 2020

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.21.10149

1 reference

19 August 2017

0 references

1 reference

PMC publication ID

50295

19 August 2017

1 reference

PMC publication ID

50295