Oxidative stress in prehypertension: rationale for antioxidant clinical trials (Q37270961)

19 August 2017

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title

Oxidative stress in prehypertension: rationale for antioxidant clinical trials (English)

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19 August 2017

Selvaraj Nambiar

1

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19 August 2017

Sathiyapriya Viswanathan

2

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19 August 2017

Bobby Zachariah

3

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19 August 2017

Nandeesha Hanumanthappa

4

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19 August 2017

Sridhar Gopalakrishna Magadi

5

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19 August 2017

15 September 2008

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19 August 2017

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19 August 2017

60

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19 August 2017

2

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19 August 2017

221-234

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Factors associated with oxidative stress in human populations

19 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Obesity and oxidative stress: a direct link to CVD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and smoking-induced vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and preeclampsia: rationale for antioxidant clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Free radicals and antioxidants in normal physiological functions and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Biomarkers of oxidative stress: an analytical approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Pathological investigation of oxidative stress in the post-genomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress induced in pathologies: the role of antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Prehypertension and cardiovascular morbidity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Prevalence of heart disease and stroke risk factors in persons with prehypertension in the United States, 1999-2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Antioxidant Activities and Oxidative Stress Byproducts in Human Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Association of increased phagocytic NADPH oxidase-dependent superoxide production with diminished nitric oxide generation in essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Blood pressure and nutrient intake in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Perinatal L-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Tempol attenuates the development of hypertensive renal injury in Dahl salt-sensitive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dietary vitamin E and C supplementation prevents fructose induced hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Anti-oxidants show an anti-hypertensive effect in diabetic and hypertensive subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Different antioxidants status, total antioxidant power and free radicals in essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Protein carbonyl groups as biomarkers of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidants and antioxidants: state of the art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

The oxidation hypothesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress as a regulator of gene expression in the vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

NAD(P)H oxidase: role in cardiovascular biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vascular oxidative stress precedes high blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Antioxidants for hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Role of macula densa NOS in tubuloglomerular feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Gene transfer of extracellular superoxide dismutase reduces arterial pressure in spontaneously hypertensive rats: role of heparin-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Acute inhibition of glutathione biosynthesis alters endothelial function and blood pressure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Increased nitric oxide inactivation by reactive oxygen species in lead-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Effect of lead on nitric oxide synthase expression in coronary endothelial cells: role of superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Lead-induced hypertension. III. Increased hydroxyl radical production

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Reactive oxygen species: roles in blood pressure and kidney function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and vascular damage in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Reactive oxygen species in vascular biology: role in arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Is prehypertension a risk factor for cardiovascular diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and cardiovascular injury: Part II: animal and human studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vascular NAD(P)H oxidases: specific features, expression, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Redox signaling and the emerging therapeutic potential of thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Molecular mechanisms of N-acetylcysteine actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Kinetic studies of covalent binding between N-acetyl-L-cysteine and human serum albumin through a mixed-disulfide using an N-methylpyridinium polymer-based column

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Mesna (2-mercaptoethane sulfonate) prevents ischemia/reperfusion induced renal oxidative damage in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Mesna: a novel renoprotective antioxidant in ischaemic acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Evidence that reactive oxygen species do not mediate NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Catalytic antioxidants: a radical approach to new therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Inhibition of airway inflammation and hyperreactivity by an antioxidant mimetic

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Superoxide dismustase mimetic tempol decreases blood pressure by increasing renal medullary blood flow in hyperinsulinemic-hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Neuroprotection by the stable nitroxide Tempol during reperfusion in a rat model of transient focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Molecular actions of Ebselen—an antiinflammatory antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Allopurinol improves endothelial dysfunction in chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Rationale, design and organisation of an efficacy and safety study of oxypurinol added to standard therapy in patients with NYHA class III - IV congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dietary lipoic acid supplementation attenuates hypertension in Dahl salt sensitive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Effects of alpha-lipoic acid on deoxycorticosterone acetate-salt-induced hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Non-antioxidant molecular functions of alpha-tocopherol (vitamin E).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Chemistry and biology of vitamin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Non-antioxidant activities of vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin E and its function in membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Tocotrienols in cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dietary vitamin E supplementation lowers blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin E can reduce blood pressure in mild hypertensives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Free radical-induced damage to DNA: mechanisms and measurement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

F2-isoprostanes as markers of oxidative stress in vivo: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

On the antioxidant effects of ascorbic acid and glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Combination oral antioxidant supplementation reduces blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

A randomized, double-blind, controlled trial of vitamin C in the management of hypertension and lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Does vitamin C reduce blood pressure? Results of a large study of people aged 65 or older.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dietary vitamin C supplementation lowers blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Antihypertensive and vasodilator actions of antioxidants in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin C blocks vascular dysfunction and release of interleukin-6 induced by endothelin-1 in humans in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

alpha-Lipoic acid as a biological antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

alpha-Lipoic acid: a metabolic antioxidant which regulates NF-kappa B signal transduction and protects against oxidative injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Collaborative Group of the Primary Prevention Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Antioxidants, statins, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin E consumption and the risk of coronary heart disease in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin E consumption and the risk of coronary disease in women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Vitamin C and blood pressure--an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Effects of vitamin E on clinic and ambulatory blood pressure in treated hypertensive patients. Collaborative Group of the Primary Prevention Project (PPP)--Hypertension study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0003319708319781

21 January 2018

Identifiers

DOI

10.1177/0003319708319781

1 reference

19 August 2017

1 reference