KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. (Q37273361)

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scientific article published on 18 September 2008

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English	KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.	scientific article published on 18 September 2008

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scholarly article

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14 January 2020

1 reference

Europe PubMed Central

KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program (English)

1 reference

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14 January 2020

colorectal carcinoma

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inferred from title

Fatima Carneiro

4

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14 January 2020

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14 January 2020

Generoso Bevilacqua

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14 January 2020

author name string

J H J M van Krieken

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14 January 2020

A Jung

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T Kirchner

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F T Bosman

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J F Fléjou

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T Plato Hansen

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G de Hertogh

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C Langner

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14 January 2020

M Ligtenberg

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14 January 2020

D Tiniakos

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S Tejpar

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14 January 2020

A Ensari

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14 January 2020

publication date

18 September 2008

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14 January 2020

Virchows Archiv

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453

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417-431

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14 January 2020

5

1 reference

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14 January 2020

https://scigraph.springernature.com/pub.10.1007/s00428-008-0665-y

0 references

Epidermal growth factor receptor is a predictor of tumor response in locally advanced rectal cancer patients treated with preoperative radiotherapy.

1 reference

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21 January 2018

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

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21 January 2018

The detection of K-ras mutations in colorectal cancer using the amplification-refractory mutation system

1 reference

https://api.crossref.org/works/10.1007%2FS00428-008-0665-Y

21 January 2018

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Typing of multiple single-nucleotide polymorphisms by a microsphere-based rolling circle amplification assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ki-ras mutations and prognosis in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serial processing of biological reactions using flow-through microfluidic devices: coupled PCR/LDR for the detection of low-abundant DNA point mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New comprehensive denaturing-gradient-gel- electrophoresis assay for KRAS mutation detection applied to paraffin-embedded tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the novel quantitative ARMS assay and an enriched PCR-ASO assay for K-ras mutations with conventional cytology on endobiliary brush cytology from 312 consecutive extrahepatic biliary stenoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR targeting of solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of EGFR expression on colorectal cancer patient prognosis and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-ras mutation detection in colorectal cancer using the Pyrosequencing technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Approaching real-time molecular diagnostics: single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant KRAS, chromosomal instability and prognosis in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR in colorectal cancer: more than a simple receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-cancer therapy with EGFR inhibitors: factors of prognostic and predictive significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrochemical detection of point mutation based on surface ligation reaction and biometallization

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of BRAF V600E mutation by pyrosequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of K-ras exon 1 mutations by constant denaturant capillary electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab for the treatment of colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of stool DNA mutations before and after treatment of colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized phase III trial results of panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAF/RAS oncogenes and mismatch-repair status

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor analyses in colorectal cancer: a comparison of methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No duplicate KRAS mutation is identified on the same allele in gastric or colorectal cancer cells with multiple KRAS mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidermal growth factor receptor as a target for colorectal cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR antagonists in cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved method for rapid screening of DNA mutations by nonradioactive single-strand conformation polymorphism procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2008

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevalence of PIK3CA mutations in gastric and colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Standardization of HER2 testing: results of an international proficiency-testing ring study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selecting patients for treatment with epidermal growth factor tyrosine kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of interactions: antiepidermal growth factor receptor agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation status of epidermal growth factor receptor is closely associated with responsiveness to gefitinib in pulmonary adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive detection through REMS-PCR technique of K-ras mutations in stool DNA of patients with colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor expression in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent KRAS codon 146 mutations in human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of a national external quality assessment scheme for breast pathology in the UK

1 reference

https://pubmed.ncbi.nlm.nih.gov/18802721

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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