Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses (Q37276902)

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scientific article published on 24 June 2009

Language	Label	Description	Also known as
English	Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses	scientific article published on 24 June 2009

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses (English)

1 reference

Europe PubMed Central

19 August 2017

author name string

Jacob T Minang

1

1 reference

Europe PubMed Central

19 August 2017

Matthew T Trivett

2

1 reference

Europe PubMed Central

19 August 2017

Lori V Coren

3

1 reference

Europe PubMed Central

19 August 2017

Eugene V Barsov

4

1 reference

Europe PubMed Central

19 August 2017

Michael Piatak

5

1 reference

Europe PubMed Central

19 August 2017

David E Ott

6

1 reference

Europe PubMed Central

19 August 2017

Claes Ohlen

7

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

24 June 2009

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

391

1 reference

Europe PubMed Central

19 August 2017

1

1 reference

Europe PubMed Central

19 August 2017

130-139

1 reference

Europe PubMed Central

19 August 2017

Toward an AIDS vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Selective downregulation of rhesus macaque and sooty mangabey major histocompatibility complex class I molecules by Nef alleles of simian immunodeficiency virus and human immunodeficiency virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2716421

6 September 2017

Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation

1 reference

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6 September 2017

Not all cytokine-producing CD8+ T cells suppress simian immunodeficiency virus replication

1 reference

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Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

1 reference

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6 September 2017

The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus

1 reference

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Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.

1 reference

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6 September 2017

Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus

1 reference

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nef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.

1 reference

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T-cell receptor:CD3 down-regulation is a selected in vivo function of simian immunodeficiency virus Nef but is not sufficient for effective viral replication in rhesus macaques

1 reference

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Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection

1 reference

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Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production

1 reference

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The advantage of early recognition of HIV-infected cells by cytotoxic T-lymphocytes

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How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?

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Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

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Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group

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Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

1 reference

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Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression

1 reference

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The explosive human immunodeficiency virus type 1 epidemic among injecting drug users of Kathmandu, Nepal, is caused by a subtype C virus of restricted genetic diversity

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The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

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Degradation of cell proteins and the generation of MHC class I-presented peptides

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Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

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HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism

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Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

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Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

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Cutting Edge: Epitope-dependent effect of Nef-mediated HLA class I down-regulation on ability of HIV-1-specific CTLs to suppress HIV-1 replication

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12 December 2020

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10.1016/J.VIROL.2009.06.008

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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