MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters (Q37288598)

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English	MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

myasthenia gravis

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5

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Angela Vincent

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Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Inga Koneczny

1

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Europe PubMed Central

PMC publication ID

19 August 2017

Judith Cossins

2

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Europe PubMed Central

PMC publication ID

19 August 2017

Patrick Waters

3

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Europe PubMed Central

PMC publication ID

19 August 2017

David Beeson

4

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Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

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publication date

7 November 2013

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Europe PubMed Central

PMC publication ID

19 August 2017

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Europe PubMed Central

PMC publication ID

19 August 2017

8

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Europe PubMed Central

PMC publication ID

19 August 2017

11

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Europe PubMed Central

PMC publication ID

19 August 2017

e80695

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Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution 4.0 International

7 November 2013

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3820634/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

CD20 antibody primes B lymphocytes for type I interferon production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The role of MuSK in synapse formation and neuromuscular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The search for new antigenic targets in myasthenia gravis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The spectrum of mutations that underlie the neuromuscular junction synaptopathy in DOK7 congenital myasthenic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Role of type I interferons in the activation of autoreactive B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Signaling and aging at the neuromuscular synapse: lessons learnt from neuromuscular diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Initiation of synapse formation by Wnt-induced MuSK endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

What is IgG4? A review of the biology of a unique immunoglobulin subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Muscle specific kinase: organiser of synaptic membrane domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The effect of plasma from muscle-specific tyrosine kinase myasthenia patients on regenerating endplates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Immunoglobulin G4: an odd antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

LRP4 serves as a coreceptor of agrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Lrp4 is a receptor for Agrin and forms a complex with MuSK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Induction of myasthenia by immunization against muscle-specific kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

The agrin hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Effects of passive antibody in bee venom anaphylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

6 September 2017

Nonprecipitating asymmetric antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

14 September 2017

Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

14 September 2017

Clinical fluctuations in MuSK myasthenia gravis are related to antigen-specific IgG4 instead of IgG1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

14 September 2017

Dok-7 mutations underlie a neuromuscular junction synaptopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

14 September 2017

Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

14 September 2017

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

28 September 2017

Long-term benefit of rituximab in MuSK autoantibody myasthenia gravis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

[Anti-MuSK antibodies in myasthenia gravis block binding of collagen Q to MuSK].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Wnt proteins regulate acetylcholine receptor clustering in muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Long-lasting treatment effect of rituximab in MuSK myasthenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4-related systemic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Anti-MuSK antibodies: correlation with myasthenia gravis severity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Myasthenia gravis induced in mice by immunization with the recombinant extracellular domain of rat muscle-specific kinase (MuSK).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Antibodies to purified bee venom proteins and peptides. II. A detailed study of changes in IgE and IgG antibodies to individual bee venom antigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

Myasthenia gravis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3820634

3 September 2018

MuSK levels differ between adult skeletal muscles and influence postsynaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased complement consumption in MuSK-antibody-positive myasthenia gravis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rituximab for the treatment of IgG4-related disease: lessons from 10 consecutive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of serum IgG4 levels by a competitive immunoenzymatic assay with monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serologic aspects of IgG4 antibodies. II. IgG4 antibodies form small, nonprecipitating immune complexes due to functional monovalency

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody heterogeneity and specificity in myasthenia gravis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed synapsing muscles are more severely affected in an experimental model of MuSK-induced myasthenia gravis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sera from AChR-antibody negative myasthenia gravis patients on AChR and MuSK in cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0080695

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Europe PubMed Central

PMC publication ID

19 August 2017

2013PLoSO...880695K

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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