Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease. (Q37292770)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19620629%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease (English)

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2 February 2020

3

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2 February 2020

Clare M. Lloyd

8

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2 February 2020

Vily Panoutsakopoulou

9

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author name string

Maria Semitekolou

1

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2 February 2020

Themis Alissafi

2

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2 February 2020

Evangelia Kourepini

4

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2 February 2020

Harsha H Kariyawasam

5

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2 February 2020

Antony B Kay

6

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2 February 2020

Douglas S Robinson

7

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2 February 2020

Georgina Xanthou

10

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2 February 2020

language of work or name

English

0 references

publication date

20 July 2009

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Journal of Experimental Medicine

2 February 2020

published in

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2 February 2020

volume

206

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issue

8

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2 February 2020

page(s)

1769-1785

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The biology of activin: recent advances in structure, regulation and function

2 February 2020

cites work

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Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent.

6 September 2017

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6 September 2017

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Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma.

6 September 2017

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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Inhibitory effect of activin A on activation of lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells

14 September 2017

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Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages

14 September 2017

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Functional analysis of activins during mammalian development.

14 September 2017

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Basal expression of bone morphogenetic protein receptor is reduced in mild asthma

28 September 2017

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26 June 2018

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Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumococcal meningitis

26 June 2018

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26 June 2018

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26 June 2018

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Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1

26 June 2018

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Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells

26 June 2018

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Activin-A attenuates several human natural killer cell functions

3 September 2018

1 reference

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Activin A down-regulates the phagocytosis of lipopolysaccharide-activated mouse peritoneal macrophages in vitro and in vivo

3 September 2018

1 reference

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A dual role of activin A in regulating immunoglobulin production of B cells

3 September 2018

1 reference

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Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production.

3 September 2018

1 reference

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Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

3 September 2018

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Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice.

3 September 2018

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Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

3 September 2018

1 reference

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Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma

3 September 2018

1 reference

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Therapeutic potential of follistatin for colonic inflammation in mice

3 September 2018

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A critical role for eosinophils in allergic airways remodeling

3 September 2018

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Defining a link with asthma in mice congenitally deficient in eosinophils.

3 September 2018

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Activin A induces cell proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.

3 September 2018

1 reference

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Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

3 September 2018

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Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082603

Acute Allergen-Induced Airway Remodeling in Atopic Asthma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082603

Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma

21 January 2018

1 reference

12 December 2020

Activin A: a novel player and inflammatory marker in inflammatory bowel disease?

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12 December 2020

Suppression of IL-6 biological activities by activin A and implications for inflammatory arthropathies

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12 December 2020

Follistatin is a candidate endogenous negative regulator of activin A in experimental allergic asthma

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12 December 2020

From vanilla to 28 flavors: multiple varieties of T regulatory cells

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12 December 2020

Remodeling and airway hyperresponsiveness but not cellular inflammation persist after allergen challenge in asthma

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12 December 2020

Emerging challenges in regulatory T cell function and biology

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12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

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12 December 2020

Activin A stimulates type IV collagenase (matrix metalloproteinase-2) production in mouse peritoneal macrophages

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12 December 2020

Identifiers

DOI

10.1084/JEM.20082603

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19620629%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19620629%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

19620629

1 reference