Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway. (Q37295219)

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scientific article published on January 2012

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English	Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway.	scientific article published on January 2012

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scholarly article

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22 January 2020

Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway (English)

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22 January 2020

apoptotic process

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inferred from title

5

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22 January 2020

author name string

Chun Hu

1

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22 January 2020

Gang Song

2

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22 January 2020

Bing Zhang

3

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22 January 2020

Zhongchen Liu

4

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22 January 2020

Hong Zhang

6

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22 January 2020

Tianhui Hu

7

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22 January 2020

publication date

1 January 2012

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22 January 2020

Journal of Cellular and Molecular Medicine

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22 January 2020

16

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22 January 2020

1

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22 January 2020

96-106

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22 January 2020

Bid stands at the crossroad of stress-response pathways

1 reference

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6 September 2017

Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons

1 reference

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6 September 2017

Transcriptional anti-angiogenesis therapy of human pancreatic cancer

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6 September 2017

Bid, a BH3-only multi-functional molecule, is at the cross road of life and death

1 reference

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6 September 2017

Global cancer statistics, 2002

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6 September 2017

Molecular basis of gastric cancer development and progression

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6 September 2017

Translocation of full-length Bid to mitochondria during anoikis

1 reference

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6 September 2017

A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage

1 reference

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6 September 2017

Induction of apoptosis by a novel intestinal metabolite of ginseng saponin via cytochrome c-mediated activation of caspase-3 protease

1 reference

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6 September 2017

Molecular biology of gastric carcinoma: from laboratory to bedside.

1 reference

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6 September 2017

Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study

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6 September 2017

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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6 September 2017

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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6 September 2017

Main ginseng saponin metabolites formed by intestinal bacteria

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6 September 2017

BID: a novel BH3 domain-only death agonist

1 reference

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6 September 2017

Association of p53 with Bid induces cell death in response to etoposide treatment in hepatocellular carcinoma

1 reference

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14 September 2017

Effect of compound K, a metabolite of ginseng saponin, combined with gamma-ray radiation in human lung cancer cells in vitro and in vivo

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14 September 2017

Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells

1 reference

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14 September 2017

Bid exhibits S phase checkpoint activation and plays a pro-apoptotic role in response to etoposide-induced DNA damage in hepatocellular carcinoma cells

1 reference

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14 September 2017

A ginsenoside metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, triggers apoptosis in activated rat hepatic stellate cells via caspase-3 activation

1 reference

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14 September 2017

Adenovirus-mediated tBid overexpression results in therapeutic effects on p53-resistant hepatocellular carcinoma.

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14 September 2017

A role for proapoptotic BID in the DNA-damage response

1 reference

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14 September 2017

Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis

1 reference

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14 September 2017

Bid sensitizes apoptosis induced by chemotherapeutic drugs in hepatocellular carcinoma.

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14 September 2017

Role of the Fas/Fas ligand death receptor pathway in ginseng saponin metabolite-induced apoptosis in HepG2 cells

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14 September 2017

A novel ginseng saponin metabolite induces apoptosis and down-regulates fibroblast growth factor receptor 3 in myeloma cells.

1 reference

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14 September 2017

A ginseng saponin metabolite suppresses tumor necrosis factor-alpha-promoted metastasis by suppressing nuclear factor-kappaB signaling in murine colon cancer cells.

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26 June 2018

Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction

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26 June 2018

An intestinal bacterial metabolite of ginseng protopanaxadiol saponins has the ability to induce apoptosis in tumor cells.

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26 June 2018

Studies on Absorption, Distribution, Excretion and Metabolism of Ginseng Saponins. VII. Comparison of the Decomposition Modes of Ginsenoside-Rb1 and -Rb2 in the Digestive Tract of Rats

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26 June 2018

Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells

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3 September 2018

Anti-diabetic effects of compound K versus metformin versus compound K-metformin combination therapy in diabetic db/db mice

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3 September 2018

Anti-proliferation and apoptosis induced by a novel intestinal metabolite of ginseng saponin in human hepatocellular carcinoma cells.

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3 September 2018

Ginsenosides compound K and Rh(2) inhibit tumor necrosis factor-alpha-induced activation of the NF-kappaB and JNK pathways in human astroglial cells.

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3 September 2018

Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression

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3 September 2018

Proapoptotic BID is an ATM effector in the DNA-damage response

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3 September 2018

Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells

1 reference

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3 September 2018

G1 phase arrest of the cell cycle by a ginseng metabolite, compound K, in U937 human monocytic leukamia cells.

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3 September 2018

Estimates of the worldwide incidence of 25 major cancers in 1990.

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3 September 2018

Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21323864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ginseng intestinal bacterial metabolite IH901 as a new anti-metastatic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/21323864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration--measurement of compound K by enzyme immunoassay

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1582-4934.2011.01278.X

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22 January 2020

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22 January 2020

1 reference

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22 January 2020

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