Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology. (Q37298654)

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24 December 2019

review article

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title

Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology (English)

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24 December 2019

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hepatocellular carcinoma

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2

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24 December 2019

Cécile Godard

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24 December 2019

author name string

Catherine Cavard

1

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24 December 2019

Virginie Audard

3

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24 December 2019

Samira Benhamouche

4

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24 December 2019

Laetitia Finzi

5

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24 December 2019

Cyril Torre

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24 December 2019

Gisèle Grimber

7

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24 December 2019

Benoit Terris

9

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24 December 2019

Christine Perret

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24 December 2019

language of work or name

English

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publication date

1 October 2008

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24 December 2019

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24 December 2019

volume

4

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24 December 2019

issue

5

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24 December 2019

page(s)

647-660

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

24 December 2019

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WNT/beta-catenin signaling in liver health and disease

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Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects

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The Wnt signaling pathway in development and disease

21 January 2018

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Mechanistic insights from structural studies of beta-catenin and its binding partners

21 January 2018

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Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

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Lessons from hereditary colorectal cancer

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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21 January 2018

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

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Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

21 January 2018

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 January 2018

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Wnt signalling induces maturation of Paneth cells in intestinal crypts

21 January 2018

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

21 January 2018

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Focus on hepatocellular carcinoma.

21 January 2018

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Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study

21 January 2018

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Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis

21 January 2018

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Genetics of hepatocellular tumors.

21 January 2018

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Hepatocellular carcinoma pathogenesis: from genes to environment

21 January 2018

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

21 January 2018

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Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

21 January 2018

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Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.

21 January 2018

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EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma

21 January 2018

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Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

21 January 2018

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

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Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

21 January 2018

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New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism

21 January 2018

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The links between axin and carcinogenesis

21 January 2018

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Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

21 January 2018

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Progenitor cells in diseased human liver

21 January 2018

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Wnt/beta-catenin signaling mediates oval cell response in rodents

21 January 2018

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Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.

21 January 2018

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A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development.

21 January 2018

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beta-Catenin is critical for early postnatal liver growth.

21 January 2018

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Apc tumor suppressor gene is the "zonation-keeper" of mouse liver

21 January 2018

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Zonation of parenchymal and nonparenchymal metabolism in liver

21 January 2018

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Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice

21 January 2018

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Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.

21 January 2018

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Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations

21 January 2018

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Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

21 January 2018

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Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations

21 January 2018

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Identification of the leukocyte cell-derived chemotaxin 2 as a direct target gene of beta-catenin in the liver.

21 January 2018

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Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/14796694.4.5.647

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18922122%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference