Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease (Q37300209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18669499%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease (English)

1 reference

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11 January 2020

0 references

1 reference

1 reference

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Rosario Sanchez-Pernaute

1

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11 January 2020

Lorenz Studer

7

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11 January 2020

Ole Isacson

8

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11 January 2020

author name string

Hyojin Lee

2

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11 January 2020

Michaela Patterson

3

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11 January 2020

Casper Reske-Nielsen

4

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11 January 2020

Takahito Yoshizaki

5

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11 January 2020

Kai C Sonntag

6

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11 January 2020

language of work or name

English

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publication date

22 July 2008

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11 January 2020

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11 January 2020

volume

131

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11 January 2020

page(s)

2127-2139

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11 January 2020

issue

Pt 8

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Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease

11 January 2020

cites work

1 reference

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6 September 2017

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Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

6 September 2017

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Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion

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Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease

6 September 2017

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Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.

6 September 2017

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6 September 2017

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A specific survival response in dopamine neurons at most risk in Parkinson's disease

6 September 2017

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Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion

6 September 2017

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Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation.

6 September 2017

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Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

6 September 2017

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Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease.

6 September 2017

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Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.

6 September 2017

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Derivation of midbrain dopamine neurons from human embryonic stem cells

6 September 2017

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Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

6 September 2017

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Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

6 September 2017

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6 September 2017

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Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity

6 September 2017

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6 September 2017

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Synaptic contacts between identified neurons visualized in the confocal laser scanning microscope. Neuroanatomical tracing combined with immunofluorescence detection of post-synaptic density proteins and target neuron-markers

6 September 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

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6 September 2017

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26 June 2018

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26 June 2018

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Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

26 June 2018

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2 September 2018

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2 September 2018

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Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.

2 September 2018

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Methylation status of imprinting centers for H19/IGF2 and SNURF/SNRPN in primate embryonic stem cells.

2 September 2018

1 reference

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BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors.

2 September 2018

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The evaluation of early embryonic neurogenesis after exposure to the genotoxic agent 5-bromo-2'-deoxyuridine in mice.

2 September 2018

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2 September 2018

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Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain.

2 September 2018

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Context-dependent neuronal differentiation and germ layer induction of Smad4-/- and Cripto-/- embryonic stem cells.

2 September 2018

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Subcellular redistribution of the synapse-associated proteins PSD-95 and SAP97 in animal models of Parkinson's disease and L-DOPA-induced dyskinesia.

2 September 2018

1 reference

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Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats

2 September 2018

1 reference

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Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

2 September 2018

1 reference

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Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

2 September 2018

1 reference

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Methylation dynamics of imprinted genes in mouse germ cells.

2 September 2018

1 reference

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In vitro generation and transplantation of precursor-derived human dopamine neurons

2 September 2018

1 reference

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Epigenetic instability in ES cells and cloned mice.

2 September 2018

1 reference

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Stem cells--hype and hope.

2 September 2018

1 reference

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The time of genesis, embryonic origin and differentiation of the brain stem monoamine neurons in the rhesus monkey.

2 September 2018

1 reference

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Large stem cell grafts could lead to erroneous interpretations of behavioral results?

2 September 2018

1 reference

12 December 2020

Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation

1 reference

12 December 2020

Restoration of complex sensorimotor behavior and skilled forelimb use by a modified nigral cell suspension transplantation approach in the rat parkinson model

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12 December 2020

Estimation of nuclear population from microtome sections

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12 December 2020

Identifiers

DOI

10.1093/BRAIN/AWN144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18669499%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18669499%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference