An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1. (Q37303911)

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5 February 2020

title

An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1. (English)

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5 February 2020

0 references

1

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5 February 2020

D. Eric Walters

5

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5 February 2020

author name string

Mikheil Nanazashvili

2

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5 February 2020

Hui Li

3

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5 February 2020

Lawrence G Palmer

4

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5 February 2020

language of work or name

English

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publication date

1 August 2009

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5 February 2020

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5 February 2020

volume

97

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5 February 2020

issue

4

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5 February 2020

page(s)

1058-1066

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

5 February 2020

cites work

1 reference

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Molecular driving forces determining potassium channel slow inactivation

6 September 2017

1 reference

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H bonding at the helix-bundle crossing controls gating in Kir potassium channels

6 September 2017

1 reference

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External K activation of Kir1.1 depends on the pH gate

6 September 2017

1 reference

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Localization of the pH gate in Kir1.1 channels.

6 September 2017

1 reference

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Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel

6 September 2017

1 reference

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Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR.

6 September 2017

1 reference

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Role of conserved glycines in pH gating of Kir1.1 (ROMK)

6 September 2017

1 reference

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Molecular determinants of gating at the potassium-channel selectivity filter

6 September 2017

1 reference

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Voltage-dependent gating at the KcsA selectivity filter

6 September 2017

1 reference

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A structural interpretation of voltage-gated potassium channel inactivation.

6 September 2017

1 reference

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Structural locus of the pH gate in the Kir1.1 inward rectifier channel.

6 September 2017

1 reference

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Regulation of Kir channels by intracellular pH and extracellular K(+): mechanisms of coupling

6 September 2017

1 reference

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Crystal structure of the potassium channel KirBac1.1 in the closed state

6 September 2017

1 reference

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Permeant cations and blockers modulate pH gating of ROMK channels.

6 September 2017

1 reference

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K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore

6 September 2017

1 reference

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Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels

6 September 2017

1 reference

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Regulation of ROMK by extracellular cations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

The barium site in a potassium channel by x-ray crystallography

6 September 2017

1 reference

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Mechanisms of inward-rectifier K+ channel inhibition by tertiapin-Q.

6 September 2017

1 reference

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Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

The moving parts of voltage-gated ion channels

6 September 2017

1 reference

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Contribution of the selectivity filter to inactivation in potassium channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

pH-dependent gating of ROMK (Kir1.1) channels involves conformational changes in both N and C termini

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Gating dependence of inner pore access in inward rectifier K(+) channels

6 September 2017

1 reference

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Dilated and defunct K channels in the absence of K+.

14 September 2017

1 reference

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Shaker B K+ conductance in Na+ solutions lacking K+ ions: a remarkably stable non-conducting state produced by membrane depolarizations

14 September 2017

1 reference

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Dynamic rearrangement of the outer mouth of a K+ channel during gating

28 September 2017

1 reference

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Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a K+ channel

28 September 2017

1 reference

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Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.

28 September 2017

1 reference

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Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels

28 September 2017

1 reference

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Pore mutations alter closing and opening kinetics in Shaker K+ channels.

26 June 2018

1 reference

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Inactivation of voltage-gated cardiac K+ channels.

26 June 2018

1 reference

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A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance, and gating.

26 June 2018

1 reference

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Ionic pores, gates, and gating currents.

26 June 2018

1 reference

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Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.

26 June 2018

1 reference

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The molecular mechanism of toxin-induced conformational changes in a potassium channel: relation to C-type inactivation.

26 June 2018

1 reference

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Molecular basis of ion selectivity, block, and rectification of the inward rectifier Kir3.1/Kir3.4 K(+) channel

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Localization of PIP2 activation gate in inward rectifier K+ channels

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Titration of tertiapin-Q inhibition of ROMK1 channels by extracellular protons

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

A conserved glutamate is important for slow inactivation in K+ channels.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Mechanisms for the time-dependent decay of inward currents through cloned Kir2.1 channels expressed in Xenopus oocytes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

A novel high-affinity inhibitor for inward-rectifier K+ channels.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Mutations in the pore region of ROMK enhance Ba2+ block.

2 September 2018

1 reference

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Extracellular K+ and intracellular pH allosterically regulate renal Kir1.1 channels.

2 September 2018

1 reference

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Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726312

Pore mutations in Shaker K+ channels distinguish between the sites of tetraethylammonium blockade and C-type inactivation

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19686653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

K+ channels close more slowly in the presence of external K+ and Rb+

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19686653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BPJ.2009.05.056

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19686653%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19686653%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

19686653

1 reference