CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration (Q37308134)

19 August 2017

CD154 deficiency uncouples allograft CD8+ T-cell effector function from proliferation and inhibits murine airway obliteration (English)

1 reference

19 August 2017

P D Shah

1

1 reference

19 August 2017

E E West

2

1 reference

19 August 2017

A B Whitlock

3

1 reference

19 August 2017

J B Orens

4

1 reference

19 August 2017

J F McDyer

5

1 reference

19 August 2017

language of work or name

English

0 references

publication date

1 December 2009

1 reference

American Journal of Transplantation

19 August 2017

1 reference

19 August 2017

9

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19 August 2017

12

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19 August 2017

2697-2706

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Chronic lung allograft rejection: mechanisms and therapy

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Critical role of CD4 help in CD154 blockade-resistant memory CD8 T cell activation and allograft rejection in sensitized recipients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Alloreactive (CD4-Independent) CD8+ T cells jeopardize long-term survival of intrahepatic islet allografts.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Registry of the International Society for Heart and Lung Transplantation: introduction to the 2007 annual reports--100,000 transplants and going strong

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

CD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus Encephalitis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Human and murine obliterative bronchiolitis in transplant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Pluripotent allospecific CD8+ effector T cells traffic to lung in murine obliterative airway disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Lung transplantation: opportunities for research and clinical advancement

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Bronchiolitis obliterans after human lung transplantation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Lymphocyte-mediated cytotoxicity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Trachea allograft class I molecules directly activate and retain CD8+ T cells that cause obliterative airways disease.

26 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

The CD154-CD40 T cell costimulation pathway is required for host sensitization of CD8(+) T cells by skin grafts via direct antigen presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2009.02805.X

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827910

Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand

20 October 2018

1 reference

12 December 2020

CD40 ligand/CD40 stimulation regulates the production of IFN-gamma from human peripheral blood mononuclear cells in an IL-12- and/or CD28-dependent manner

1 reference

12 December 2020

T-cell and major histocompatibility complex requirements for obliterative airway disease in heterotopically transplanted murine tracheas

1 reference

12 December 2020

Instillation of allogeneic lung macrophages and dendritic cells cause differential effects on local IFN-gamma production, lymphocytic bronchitis, and vasculitis in recipient murine lungs

1 reference

12 December 2020

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

12 December 2020

Induction of obliterative airway disease in murine tracheal allografts by CD8+ CTLs recognizing a single minor histocompatibility antigen

1 reference

12 December 2020

CD4 T cell-dependent conditioning of dendritic cells to produce IL-12 results in CD8-mediated graft rejection and avoidance of tolerance

1 reference

12 December 2020

Inhibition of obliterative airway disease development following heterotopic murine tracheal transplantation by costimulatory molecule blockade using anti-CD40 ligand alone or in combination with donor bone marrow

1 reference

12 December 2020

Intracellular cytokine optimization and standard operating procedure

1 reference

12 December 2020

Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?

1 reference

12 December 2020

Treatment with the humanized CD154-specific monoclonal antibody, hu5C8, prevents acute rejection of primary skin allografts in nonhuman primates

1 reference

12 December 2020

CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets

1 reference

12 December 2020

CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection

1 reference

12 December 2020

CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade

1 reference

12 December 2020

Dependence of murine obstructive airway disease on CD40 ligand

1 reference

12 December 2020

Different kinetics of obliterative airway disease development in heterotopic murine tracheal allografts induced by CD4+ and CD8+ T cells

1 reference

12 December 2020

Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy

1 reference

12 December 2020

CD154 on the surface of CD4+CD25+ regulatory t cells contributes to skin transplant tolerance

1 reference

12 December 2020

CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines leading to T-cell transmigration

1 reference

12 December 2020

Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms

1 reference

12 December 2020

10.1111/J.1600-6143.2009.02805.X

Identifiers

DOI

1 reference

19 August 2017

1 reference

19 August 2017

1 reference