Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds (Q37310087)

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scientific article published on 29 August 2013

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English	Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds	scientific article published on 29 August 2013

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scholarly article

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8 March 2020

Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds (English)

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Europe PubMed Central

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8 March 2020

Carlotta Granchi

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8 March 2020

Tiziano Tuccinardi

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8 March 2020

Adriano Martinelli

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8 March 2020

Filippo Minutolo

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8 March 2020

Paul J. Hergenrother

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Paul J Hergenrother

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8 March 2020

Emilia C Calvaresi

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Emilia C Calvaresi

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8 March 2020

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Ilaria Paterni

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8 March 2020

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Marco Macchia

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8 March 2020

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29 August 2013

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8 March 2020

Organic and Biomolecular Chemistry

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8 March 2020

11

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8 March 2020

38

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8 March 2020

6588-6596

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8 March 2020

Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors

1 reference

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MM/GBSA binding energy prediction on the PDBbind data set: successes, failures, and directions for further improvement.

1 reference

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6 September 2017

LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma

1 reference

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6 September 2017

Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma

1 reference

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6 September 2017

Anticancer agents that counteract tumor glycolysis.

1 reference

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6 September 2017

Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

6 September 2017

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

6 September 2017

On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.

1 reference

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6 September 2017

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

1 reference

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6 September 2017

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

6 September 2017

On the Origin of Cancer Cells

1 reference

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6 September 2017

Improved protein-ligand docking using GOLD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

6 September 2017

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

1 reference

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6 September 2017

Lactate dehydrogenase M-subunit deficiency: a new type of hereditary exertional myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

6 September 2017

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

14 September 2017

Sulforhodamine B colorimetric assay for cytotoxicity screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828658

2 September 2018

Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum

1 reference

https://api.crossref.org/works/10.1039%2FC3OB40870A

21 January 2018

2-(3-Oxo-1,3-diphenylpropyl)malonic Acids as Potent Allosteric Ligands of the PIF Pocket of Phosphoinositide-Dependent Kinase-1: Development and Prodrug Concept

1 reference

https://api.crossref.org/works/10.1039%2FC3OB40870A

21 January 2018

Inhibition of Aerobic Glycolysis in Yoshida Ascites Hepatoma by Tartronic Acid

1 reference

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21 January 2018

Identifiers

10.1039/C3OB40870A

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23986182%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23986182%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23986182%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

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