Proteomics studies reveal important information on small molecule therapeutics: a case study on plasma proteins (Q37313554)

19 August 2017

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title

Proteomics studies reveal important information on small molecule therapeutics: a case study on plasma proteins (English)

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19 August 2017

Lello Zolla

1

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19 August 2017

7 November 2008

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19 August 2017

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19 August 2017

13

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19 August 2017

23-24

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19 August 2017

1042-1051

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The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome.

19 August 2017

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Comparative plasma proteome analysis of lymphoma-bearing SJL mice

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Proteomic characterization of inter-alpha inhibitor proteins from human plasma

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Signaling--2000 and beyond

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Multi-component immunoaffinity subtraction chromatography: an innovative step towards a comprehensive survey of the human plasma proteome

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Accurate annotation of peptide modifications through unrestrictive database search

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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

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Protein microarrays as tools for functional proteomics

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UniHI: an entry gate to the human protein interactome

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A novel four-dimensional strategy combining protein and peptide separation methods enables detection of low-abundance proteins in human plasma and serum proteomes.

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Identifying pharmacodynamic protein markers of centrally active drugs in humans: a pilot study in a novel clinical model

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Strategies for plasma proteomic profiling of cancers

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Proteomics and disease--the challenges for technology and discovery

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Relationship between vitamin D binding protein and aspirin resistance in coronary ischemic patients: a proteomic study

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A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

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The ABC's (and XYZ's) of peptide sequencing

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HUPO Plasma Proteome Project: challenges and future directions

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Differences among techniques for high-abundant protein depletion

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Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: applications in diabetes and cancer

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Peptide and protein drug delivery to and into tumors: challenges and solutions

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Proteomic strategies for individualizing therapy of acute myeloid leukemia (AML).

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Toxicoproteomics: serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection

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Proteomic analysis of plasma proteins of workers exposed to benzene

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Antibody arrays in cancer research

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Composition of the peptide fraction in human blood plasma: database of circulating human peptides

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12 December 2020

Clinical proteomics: translating benchside promise into bedside reality

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Quantitative phosphoproteomic analysis of signaling network dynamics.

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High-content single-cell drug screening with phosphospecific flow cytometry

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Protein biomarkers in the plasma of workers occupationally exposed to polycyclic aromatic hydrocarbons

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Mass spectrometry-based proteomics

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Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

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Technologies and methods for sample pretreatment in efficient proteome and peptidome analysis

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Technology insight: pharmacoproteomics for cancer--promises of patient-tailored medicine using protein microarrays

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Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

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From genomics to proteomics

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The Human Red Blood Cell Proteome and Interactome

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Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors.

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12 December 2020

An investigation into the human serum "interactome"

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12 December 2020

Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A.

1 reference

12 December 2020

Calorimetry outside the box: a new window into the plasma proteome.

1 reference

12 December 2020

Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry

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12 December 2020

Mining the plasma proteome for cancer biomarkers

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Mass spectrometry-based clinical proteomics

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Oxidation of proteins: Basic principles and perspectives for blood proteomics

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12 December 2020

Immunoaffinity separation of plasma proteins by IgY microbeads: meeting the needs of proteomic sample preparation and analysis

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Progress in protein and antibody microarray technology

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Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine

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12 December 2020

Alpha cell function in health and disease: influence of glucagon-like peptide-1.

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12 December 2020

Characterization of the human blood plasma proteome

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12 December 2020

Dysregulation of retinoid transporters expression in body fluids of schizophrenia patients.

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12 December 2020

Protein biomarker discovery and validation: the long and uncertain path to clinical utility

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12 December 2020

Protein biochips: A new and versatile platform technology for molecular medicine

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Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry.

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12 December 2020

Prefractionation, enrichment, desalting and depleting of low volume and low abundance proteins and peptides using the MF10.

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12 December 2020

Clinical proteomics: revolutionizing disease detection and patient tailoring therapy

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12 December 2020

The application of inductively coupled plasma mass spectrometry in pharmaceutical and biomedical analysis

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12 December 2020

The Human Proteome Organization Plasma Proteome Project pilot phase: reference specimens, technology platform comparisons, and standardized data submissions and analyses

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Utilizing human blood plasma for proteomic biomarker discovery

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12 December 2020

Effects of genetic engineering on the pharmacokinetics of antibodies.

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12 December 2020

The impact of systems approaches on biological problems in drug discovery

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12 December 2020

Two-dimensional separation of human plasma proteins using iterative free-flow electrophoresis

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12 December 2020

Proteomics of organelles and large cellular structures

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Experimental design and analysis of antibody microarrays: applying methods from cDNA arrays

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Evaluation of multiprotein immunoaffinity subtraction for plasma proteomics and candidate biomarker discovery using mass spectrometry.

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Pharmacogenomics and pharmacoproteomics in the evaluation and management of short stature

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The ProteoMiner in the proteomic arena: a non-depleting tool for discovering low-abundance species

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Protein chip technology

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12 December 2020

Proteomics-driven cancer biomarker discovery: looking to the future.

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Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry

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12 December 2020

Transfusion medicine in the era of proteomics

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Proteomic analysis of RBC membrane protein degradation during blood storage.

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A graph-theoretic approach to testing associations between disparate sources of functional genomics data

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12 December 2020

10.1016/J.DRUDIS.2008.09.013

Identifiers

DOI

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19 August 2017

1 reference

PubMed ID

18973825