ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan (Q37317424)

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scientific article published on 05 June 2009

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English	ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan	scientific article published on 05 June 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan (English)

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19 August 2017

type 2 diabetes

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Marcus Ståhlman

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Marcus Ståhlman

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Matej Oresic

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14

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Jan Borén

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19 August 2017

Sven-Olof Olofsson

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Sven-Olof Olofsson

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Olov Wiklund

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Marja-Riitta Taskinen

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Marja-Riitta Taskinen

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Lillemor Mattsson Hultén

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Lillemor Mattsson Hultén

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19 August 2017

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Anne Hiukka

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Camilla Pettersson

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19 August 2017

Malin Levin

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Martin Adiels

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Susanne Teneberg

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19 August 2017

Eeva S Leinonen

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Kim Ekroos

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5 June 2009

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58

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9

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19 August 2017

2018-2026

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19 August 2017

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 August 2021

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A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection

1 reference

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6 September 2017

Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in KBr.

1 reference

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6 September 2017

Group v secretory phospholipase A2 promotes atherosclerosis: evidence from genetically altered mice

1 reference

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6 September 2017

A proteomic study of the apolipoproteins in LDL subclasses in patients with the metabolic syndrome and type 2 diabetes

1 reference

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6 September 2017

Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer

1 reference

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6 September 2017

Structure of low density lipoprotein (LDL) particles: basis for understanding molecular changes in modified LDL.

1 reference

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6 September 2017

Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3

1 reference

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6 September 2017

Identification of the principal proteoglycan-binding site in LDL. A single-point mutation in apo-B100 severely affects proteoglycan interaction without affecting LDL receptor binding

1 reference

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6 September 2017

Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

1 reference

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6 September 2017

Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E

1 reference

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Diet-induced obese mice develop peripheral, but not central, resistance to leptin

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6 September 2017

Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins.

1 reference

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6 September 2017

Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

6 September 2017

Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

6 September 2017

Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves pertussis toxin-sensitive G protein- and protein kinase C alpha-mediated nuclear factor-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

14 September 2017

Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

14 September 2017

An abnormal triglyceride-rich lipoprotein containing excess sialylated apolipoprotein C-III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

14 September 2017

Rapid separation and quantitation of combined neutral and polar lipid classes by high-performance liquid chromatography and evaporative light-scattering mass detection

1 reference

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26 June 2018

Comparison of the glycolipid-binding specificities of cholera toxin and porcineEscherichia coli heat-labile enterotoxin: identification of a receptor-active non-ganglioside glycolipid for the heat-labile toxin in infant rabbit small intestine

1 reference

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26 June 2018

The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

26 June 2018

Sphingomyelinase treatment of low density lipoprotein and cultured cells results in enhanced processing of LDL which can be modulated by sphingomyelin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

26 June 2018

Long-term effects of fenofibrate on VLDL and HDL subspecies in participants with type 2 diabetes mellitus.

1 reference

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2 September 2018

Apolipoprotein C-III isoforms: kinetics and relative implication in lipid metabolism.

1 reference

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Sphingomyelinase induces aggregation and fusion of small very low-density lipoprotein and intermediate-density lipoprotein particles and increases their retention to human arterial proteoglycans

1 reference

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Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensit

1 reference

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2 September 2018

Modification of LDL with human secretory phospholipase A(2) or sphingomyelinase promotes its arachidonic acid-releasing propensity

1 reference

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2 September 2018

Molecular mechanism for changes in proteoglycan binding on compositional changes of the core and the surface of low-density lipoprotein-containing human apolipoprotein B100.

1 reference

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2 September 2018

Apolipoprotein C-III isofocusing in the diagnosis of genetic defects in O-glycan biosynthesis

1 reference

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2 September 2018

Hypertriglyceridemia but not diabetes status is associated with VLDL containing apolipoprotein CIII in patients with coronary heart disease

1 reference

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2 September 2018

LDL containing apolipoprotein CIII is an independent risk factor for coronary events in diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

2 September 2018

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

2 September 2018

Role of group IIa and group V secretory phospholipases A(2) in the metabolism of lipoproteins. Substrate specificities of the enzymes and the regulation of their activities by sphingomyelin

1 reference

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2 September 2018

Distinct patterns of lipoproteins with apoB defined by presence of apoE or apoC-III in hypercholesterolemia and hypertriglyceridemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

2 September 2018

Effects of estrogenic oral contraceptives on the lipoprotein B particle system defined by apolipoproteins E and C-III content.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

2 September 2018

Human lysosomal sphingomyelinase: substrate efficacy of apolipoprotein/sphingomyelin complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2731525

2 September 2018

Insulin therapy induces antiatherogenic changes of serum lipoproteins in noninsulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular packing of high-density and low-density lipoprotein surface lipids and apolipoprotein A-I binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein C-III0 lacks carbohydrate residues: use of mass spectrometry to study apolipoprotein structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dietary fats on the fluidity of human high-density lipoprotein: influence of the overall composition and phospholipid fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid isolation of low density lipoprotein (LDL) subfractions from plasma by density gradient ultracentrifugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganglioside extraction from erythrocytes: a comparison study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory Zn2+-dependent sphingomyelinase activity in the serum of patients with type 2 diabetes is elevated

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutual modulation of sphingomyelinase and phospholipase A2 activities against mixed lipid monolayers by their lipid intermediates and glycosphingolipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of specific apolipoprotein C-III isoforms on the binding of triglyceride-rich lipoproteins to the lipolysis-stimulated receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sphingomyelin and phosphatidylcholine degradation on cyclodextrin-mediated cholesterol efflux in cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase A(2) modification of low density lipoproteins forms small high density particles with increased affinity for proteoglycans and glycosaminoglycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid turnover of apolipoprotein C-III-containing triglyceride-rich lipoproteins contributing to the formation of LDL subfractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.2337/DB09-0206

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Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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