Phosphorylation of WASp is a key regulator of activity and stability in vivo (Q37329019)

19 August 2017

Phosphorylation of WASp is a key regulator of activity and stability in vivo (English)

1 reference

19 August 2017

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Gerben Bouma

2

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Dale Moulding

Dale A Moulding

8

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Lisa Westerberg

Lisa S Westerberg

7

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Siobhan O Burns

Siobhan O Burns

14

0 references

Gareth E. Jones

Gareth E Jones

12

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Adrian Thrasher

Adrian J Thrasher

15

0 references

Austen Worth

4

Austen Worth

1 reference

19 August 2017

3

Joao Metelo

1 reference

19 August 2017

5

Yolanda Calle

1 reference

19 August 2017

1

Michael P Blundell

1 reference

19 August 2017

10

Christine Kinnon

1 reference

19 August 2017

Lucy A Cowell

6

1 reference

19 August 2017

Samuel Mirando

9

1 reference

19 August 2017

Giles O Cory

11

1 reference

19 August 2017

Scott B Snapper

13

1 reference

19 August 2017

language of work or name

English

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publication date

1 September 2009

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Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

1 reference

19 August 2017

106

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19 August 2017

37

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19 August 2017

15738-15743

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A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene.

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Inhibition of calpain stabilises podosomes and impairs dendritic cell motility

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Involvement of the Wiskott-Aldrich syndrome protein and other actin regulatory adaptors in T cell activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Cell motility under the microscope: Vorsprung durch Technik

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

THE MECHANISM OF ADHESION OF CELLS TO GLASS. A Study by Interference Reflection Microscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

WASp in immune-system organization and function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Sustained activation of N-WASP through phosphorylation is essential for neurite extension

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

WIP regulates the stability and localization of WASP to podosomes in migrating dendritic cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736139

Structure of the N-WASP EVH1 Domain-WIP Complex

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0904346106

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0904346106

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

21 January 2018

1 reference

12 December 2020

Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption

1 reference

12 December 2020

Quantifying cell-matrix adhesion dynamics in living cells using interference reflection microscopy

1 reference

12 December 2020

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis

1 reference

12 December 2020

Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0904346106

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

19805221

1 reference