Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection (Q37331568)

19 August 2017

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. (English)

1 reference

pattern recognition receptors

19 August 2017

1 reference

1 reference

Fabiola Osorio

2

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Luís F. Moita

Luis Ferreira Moita

11

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Philip R Taylor

Philip R Taylor

12

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Caetano Reis e Sousa

Caetano Reis e Sousa

13

0 references

Victor Tybulewicz

Victor Tybulewicz

9

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Jürgen Ruland

Jürgen Ruland

8

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author name string

Matthew J Robinson

1

1 reference

19 August 2017

Marcela Rosas

3

1 reference

19 August 2017

Rui P Freitas

4

1 reference

19 August 2017

Edina Schweighoffer

5

1 reference

19 August 2017

Olaf Gross

6

1 reference

19 August 2017

J Sjef Verbeek

7

1 reference

19 August 2017

Gordon D Brown

10

1 reference

19 August 2017

language of work or name

English

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publication date

24 August 2009

1 reference

Journal of Experimental Medicine

19 August 2017

1 reference

19 August 2017

206

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19 August 2017

9

1 reference

19 August 2017

2037-2051

1 reference

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

6 September 2017

1 reference

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Cell mediated immunity to fungi: a reassessment

6 September 2017

1 reference

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C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

6 September 2017

1 reference

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Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells

6 September 2017

1 reference

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DC activated via dectin-1 convert Treg into IL-17 producers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Mincle is an ITAM-coupled activating receptor that senses damaged cells

6 September 2017

1 reference

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Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

6 September 2017

1 reference

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CLEC5A is critical for dengue-virus-induced lethal disease

6 September 2017

1 reference

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The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

6 September 2017

1 reference

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C-type lectin receptors in antifungal immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

An integrated model of the recognition of Candida albicans by the innate immune system.

6 September 2017

1 reference

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Innate recognition of viruses

6 September 2017

1 reference

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

6 September 2017

1 reference

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The role of the beta-glucan receptor Dectin-1 in control of fungal infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Signaling pathways downstream of pattern-recognition receptors and their cross talk

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1 is required for beta-glucan recognition and control of fungal infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Myeloid C-type lectins in innate immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Pathogen recognition and innate immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1: a signalling non-TLR pattern-recognition receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Activation of dendritic cells: translating innate into adaptive immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dendritic cell immunoactivating receptor, a novel C-type lectin immunoreceptor, acts as an activating receptor through association with Fc receptor gamma chain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

6 September 2017

1 reference

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Immune recognition. A new receptor for beta-glucans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells

6 September 2017

1 reference

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Resistance of Fc receptor- deficient mice to fatal glomerulonephritis.

6 September 2017

1 reference

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Approaching the asymptote? Evolution and revolution in immunology

6 September 2017

1 reference

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dendritic cell interaction with Candida albicans critically depends on N-linked mannan.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Induction of CD8+ T cell responses through targeting of antigen to Dectin-2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Immunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

The macrophage mannose receptor induces IL-17 in response to Candida albicans.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

IL-17/Th17 in anti-fungal immunity: what's new?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Memory Th-17 cells specific for C. albicans are persistent in human peripheral blood.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

Involvement of Dectin-2 in Ultraviolet Radiation-Induced Tolerance

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737172

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082818

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082818

IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20082818

Candida albicans phospholipomannan is sensed through toll-like receptors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19703985

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20082818

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

19703985

1 reference