Design of efficient DNAzymes against muscle AChR alpha-subunit cRNA in vitro and in HEK 293 cells. (Q37331642)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19771209%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Design of efficient DNAzymes against muscle AChR alpha-subunit cRNA in vitro and in HEK 293 cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19771209%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

0 references

4

Kazunari Taira

1 reference

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8 February 2020

author name string

Amr Abdelgany

1

1 reference

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8 February 2020

M Khabir Uddin

2

1 reference

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8 February 2020

Matthew Wood

3

1 reference

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8 February 2020

David Beeson

5

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8 February 2020

publication date

14 October 2005

1 reference

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Journal of R N A i and Gene Silencing

8 February 2020

published in

1 reference

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8 February 2020

volume

1

1 reference

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8 February 2020

issue

2

1 reference

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8 February 2020

page(s)

88-96

1 reference

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Current understanding of congenital myasthenic syndromes

8 February 2020

cites work

1 reference

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6 September 2017

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DNAzymes: from creation in vitro to application in vivo.

6 September 2017

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Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents

6 September 2017

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RNA cleaving '10-23' DNAzymes with enhanced stability and activity

6 September 2017

1 reference

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A helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference

6 September 2017

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DNAzymes: cutting a path to a new class of therapeutics

6 September 2017

1 reference

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Design and characterization of decoy oligonucleotides containing locked nucleic acids

6 September 2017

1 reference

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Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I.

6 September 2017

1 reference

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In vitro-selected RNA cleaving DNA enzymes from a combinatorial library are potent inhibitors of HIV-1 gene expression

6 September 2017

1 reference

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The influence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme.

6 September 2017

1 reference

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Inhibition of influenza virus replication in cultured cells by RNA-cleaving DNA enzyme

6 September 2017

1 reference

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Targeted cleavage of HIV-1 coreceptor-CXCR-4 by RNA-cleaving DNA-enzyme: inhibition of coreceptor function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Mutations in different functional domains of the human muscle acetylcholine receptor alpha subunit in patients with the slow-channel congenital myasthenic syndrome

6 September 2017

1 reference

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A general purpose RNA-cleaving DNA enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Specificity of hammerhead ribozyme cleavage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

The effect of base mismatches in the substrate recognition helices of hammerhead ribozymes on binding and catalysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

A small modified hammerhead ribozyme and its conformational characteristics determined by mutagenesis and lattice calculation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Novel mono- and di-DNA-enzymes targeted to cleave TAT or TAT-REV RNA inhibit HIV-1 gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Selective DNAzyme-mediated cleavage of AChR mutant transcripts by targeting the mutation site or through mismatches in the binding arm.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Gaining target access for deoxyribozymes.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Suppression of platelet-type 12-lipoxygenase activity in human erythroleukemia cells by an RNA-cleaving DNAzyme

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737201

Inhibition of hepatitis C virus-directed gene expression by a DNA ribonuclease

2 September 2018

1 reference

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Extraordinary enhancement of the cleavage activity of a DNA-armed hammerhead ribozyme at elevated concentrations of Mg2+ ions

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19771209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of metal-ion-dependent cleavages of RNA by a DNA enzyme and a hammerhead ribozyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19771209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19771209%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

19771209

1 reference