Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies (Q37332754)

19 August 2017

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title

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies (English)

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genome-wide association study

19 August 2017

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Jennifer A Kelly

5

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John B. Harley

series ordinal

4

object named as

John B Harley

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19 August 2017

3

Carl D Langefeld

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19 August 2017

Isaac T W Harley

1

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PMCID

2737697

19 August 2017

Kenneth M Kaufman

series ordinal

2

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19 August 2017

1 May 2009

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19 August 2017

Nature Reviews Genetics

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19 August 2017

10

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19 August 2017

5

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19 August 2017

285-290

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https://scigraph.springernature.com/pub.10.1038/nrg2571

19 August 2017

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cites work

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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

6 September 2017

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A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus

6 September 2017

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Developments in the scientific understanding of lupus

6 September 2017

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Trex1 prevents cell-intrinsic initiation of autoimmunity

6 September 2017

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Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus

6 September 2017

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Genome-wide association studies for complex traits: consensus, uncertainty and challenges

6 September 2017

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Common variants within MECP2 confer risk of systemic lupus erythematosus

6 September 2017

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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

6 September 2017

1 reference

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Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

6 September 2017

1 reference

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PTPN22: its role in SLE and autoimmunity

6 September 2017

1 reference

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Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

6 September 2017

1 reference

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Identification of two independent risk factors for lupus within the MHC in United Kingdom families

6 September 2017

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A genome-wide study of lupus: preliminary analysis and data release

6 September 2017

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High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

6 September 2017

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Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European A

6 September 2017

1 reference

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Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Ethnic and geographical differences in systemic lupus erythematosus: an overview

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

PTPN22: setting thresholds for autoimmunity

6 September 2017

1 reference

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

6 September 2017

1 reference

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Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

6 September 2017

1 reference

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Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

6 September 2017

1 reference

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What have we learned from a 10-year experience with the LUMINA (Lupus in Minorities; Nature vs. nurture) cohort? Where are we heading?

6 September 2017

1 reference

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The International HapMap Project

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

C1q, autoimmunity and apoptosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

The 1982 revised criteria for the classification of systemic lupus erythematosus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0 ng/ml or lower

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Prevalence of a mutation causing C2 deficiency in systemic lupus erythematosus.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

A revised estimate of twin concordance in systemic lupus erythematosus

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Immune Interferon in the Circulation of Patients with Autoimmune Disease

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Genetic variation in the CRP promoter: association with systemic lupus erythematosus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Sex differences in autoimmune disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Human alloantibody anti-Mart interferes with Mac-1-dependent leukocyte adhesion

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

MicroRNA expression in lymphocyte development and malignancy

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

Genetic linkage and association of Fc? receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737697

3 December 2018

Identifiers

DOI

10.1038/NRG2571

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

2737697