Prevention of obesity and insulin resistance by estrogens requires ERα activation function-2 (ERαAF-2), whereas ERαAF-1 is dispensable (Q37333586)

19 August 2017

Prevention of obesity and insulin resistance by estrogens requires ERα activation function-2 (ERαAF-2), whereas ERαAF-1 is dispensable (English)

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19 August 2017

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8

Pierre Chambon

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Andrée Krust

7

object named as

Andrée Krust

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19 August 2017

10

Pierre Gourdy

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19 August 2017

9

Jean-François Arnal

1 reference

19 August 2017

Sandra Handgraaf

1

1 reference

19 August 2017

Elodie Riant

2

1 reference

19 August 2017

Aurélie Fabre

3

1 reference

19 August 2017

Aurélie Waget

4

1 reference

19 August 2017

Rémy Burcelin

5

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19 August 2017

Philippe Lière

6

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19 August 2017

language of work or name

English

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publication date

31 July 2013

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19 August 2017

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19 August 2017

62

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19 August 2017

12

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19 August 2017

4098-4108

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

19 August 2017

start time

30 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3837069/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance

6 September 2017

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Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression

6 September 2017

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6 September 2017

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Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction

6 September 2017

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Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators

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Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing

6 September 2017

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Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice

6 September 2017

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Membrane-initiated actions of estrogen on the endothelium

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The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol

6 September 2017

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Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse

6 September 2017

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Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice

6 September 2017

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Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

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Structure-function relationship of estrogen receptor alpha and beta: impact on human health

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Muscle GLUT4 regulation by estrogen receptors ERbeta and ERalpha

6 September 2017

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Integration of the extranuclear and nuclear actions of estrogen

6 September 2017

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Coregulator function: a key to understanding tissue specificity of selective receptor modulators

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Full Activation of Estrogen Receptor α Activation Function-1 Induces Proliferation of Breast Cancer Cells

6 September 2017

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Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains

6 September 2017

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The role of estrogen and estrogen receptor-alpha in male adipose tissue

6 September 2017

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Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.

6 September 2017

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Increased adipose tissue in male and female estrogen receptor-alpha knockout mice

6 September 2017

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Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes

6 September 2017

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Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1

6 September 2017

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Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

6 September 2017

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The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

6 September 2017

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Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

6 September 2017

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Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man

6 September 2017

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The human estrogen receptor has two independent nonacidic transcriptional activation functions

6 September 2017

1 reference

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Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial.

6 September 2017

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The relative contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha transcriptional activity depends upon the differentiation stage of the cell

14 September 2017

1 reference

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Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen

14 September 2017

1 reference

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Insulin sensitivity and cardiovascular risk factors in ovariectomized monkeys with estradiol alone or combined with nomegestrol acetate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Participation of ERalpha and ERbeta in glucose homeostasis in skeletal muscle and white adipose tissue

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Gonadal hormones determine sensitivity to central leptin and insulin.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

The effect of conjugated equine oestrogen on diabetes incidence: the Women's Health Initiative randomised trial

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trial

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837069

Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography-mass spectrometry

3 December 2018

1 reference

12 December 2020

Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae

1 reference

12 December 2020

The effects of oestrogen and progesterone on insulin sensitivity in female rats

1 reference

12 December 2020

Estrogen receptor null mice: what have we learned and where will they lead us?

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12 December 2020

Identifiers

DOI

10.2337/DB13-0282

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

23903353

1 reference