Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells (Q37333944)

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scientific article published on 08 July 2009

Language	Label	Description	Also known as
English	Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells	scientific article published on 08 July 2009

Statements

scholarly article

1 reference

Europe PubMed Central

19 August 2017

Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells (English)

1 reference

Europe PubMed Central

19 August 2017

Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Lucy Golden-Mason

1

object named as

Lucy Golden-Mason

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8

object named as

Vijay Kuchroo

1 reference

Europe PubMed Central

19 August 2017

author name string

Lucy Golden-Mason

1

1 reference

Europe PubMed Central

19 August 2017

Brent E Palmer

2

1 reference

Europe PubMed Central

19 August 2017

Nasim Kassam

3

1 reference

Europe PubMed Central

19 August 2017

Lisa Townshend-Bulson

4

1 reference

Europe PubMed Central

19 August 2017

Stephen Livingston

5

1 reference

Europe PubMed Central

19 August 2017

Brian J McMahon

6

1 reference

Europe PubMed Central

19 August 2017

Nicole Castelblanco

7

1 reference

Europe PubMed Central

19 August 2017

David R Gretch

9

1 reference

Europe PubMed Central

19 August 2017

Hugo R Rosen

10

1 reference

Europe PubMed Central

19 August 2017

language of work or name

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publication date

8 July 2009

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Europe PubMed Central

19 August 2017

Journal of Virology

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Europe PubMed Central

19 August 2017

83

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Europe PubMed Central

19 August 2017

9122-9130

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Europe PubMed Central

19 August 2017

18

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Europe PubMed Central

19 August 2017

Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Novel strategies to eliminate persistent viral infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

PD-1 and its ligands in T-cell immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Global epidemiology of hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

9 September 2017

TIMs: central regulators of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

26 June 2018

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

26 June 2018

Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: correlation with clinical disease stages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2738247

2 September 2018

Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19587053

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00639-09

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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