Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations? (Q37335840)

19 August 2017

Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations? (English)

1 reference

19 August 2017

0 references

0 references

Gloria Wong

1

0 references

Jacobus Ungerer

Jacobus Ungerer

5

0 references

Jason A. Roberts

Jason A Roberts

7

0 references

Jeffrey Lipman

Jeffrey Lipman

6

0 references

Brett C McWhinney

4

Brett McWhinney

1 reference

19 August 2017

3

Syamhanin Adnan

1 reference

19 August 2017

2

Scott Briscoe

1 reference

PMC publication ID

3837907

19 August 2017

language of work or name

English

0 references

publication date

30 September 2013

1 reference

Antimicrobial Agents and Chemotherapy

19 August 2017

1 reference

19 August 2017

57

1 reference

19 August 2017

12

1 reference

19 August 2017

6165-6170

1 reference

β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: a structured review

6 September 2017

1 reference

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The Retrospective Cohort of Extended-Infusion Piperacillin-Tazobactam (RECEIPT) study: a multicenter study.

6 September 2017

1 reference

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Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Pharmacodynamics of empirical antibiotic monotherapies for an intensive care unit (ICU) population based on Canadian surveillance data

6 September 2017

1 reference

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Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in intensive care units: analysis of data from the saline versus albumin fluid evaluation (SAFE) study

6 September 2017

1 reference

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Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis

6 September 2017

1 reference

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Applying the right statistics: analyses of measurement studies

6 September 2017

1 reference

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Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients

6 September 2017

1 reference

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Prediction of creatinine clearance from serum creatinine

6 September 2017

1 reference

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Pharmacokinetics and pharmacodynamics of meropenem in febrile neutropenic patients with bacteremia

6 September 2017

1 reference

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The phenomenon of the acute phase response

14 September 2017

1 reference

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The pharmacology of meropenem, a new carbapenem antibiotic

14 September 2017

1 reference

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Optimal meropenem concentrations to treat multidrug-resistant Pseudomonas aeruginosa septic shock

28 September 2017

1 reference

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Pharmacokinetics of once-daily dosing of ertapenem in critically ill patients with severe sepsis

26 June 2018

1 reference

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Clearance of ceftriaxone in critical care patients with acute renal failure.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

The clinical relevance of plasma protein binding changes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Pharmacokinetics and protein binding of cefazolin in morbidly obese patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Therapeutic drug monitoring of beta-lactams for critically ill patients: unwarranted or essential?

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

International study of the prevalence and outcomes of infection in intensive care units

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Protein binding of flucloxacillin in neonates

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Impact of adequate empirical antibiotic therapy on the outcome of patients admitted to the intensive care unit with sepsis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Ceftriaxone pharmacokinetics during iatrogenic hydroxyethyl starch-induced hypoalbuminemia: a model to explore the effects of decreased protein binding capacity on highly bound drugs.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Effects of concentration-dependent plasma protein binding on ceftriaxone kinetics.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837907

Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime

2 September 2018

1 reference

12 December 2020

Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial

1 reference

12 December 2020

The influence of protein binding upon tissue fluid levels of six beta-lactam antibiotics

1 reference

12 December 2020

Effect of protein binding on antibiotic activity in vivo

1 reference

12 December 2020

The contribution of pharmacokinetic-pharmacodynamic modelling with Monte Carlo simulation to the development of susceptibility breakpoints for Neisseria meningitidis

1 reference

12 December 2020

Empiric therapy for secondary peritonitis: a pharmacodynamic analysis of cefepime, ceftazidime, ceftriaxone, imipenem, levofloxacin, piperacillin/tazobactam, and tigecycline using Monte Carlo simulation

1 reference

12 December 2020

Assessment of interindividual variability of plasma concentrations after administrazion of high doses of intravenous amoxicillin or cloxacillin in critically ill patients

1 reference

12 December 2020

Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Burns Patients—A One-Year Prospective Study

1 reference

12 December 2020

Subtherapeutic Initial β-Lactam Concentrations in Select Critically Ill Patients

1 reference

12 December 2020

A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00951-13

1 reference

19 August 2017

1 reference

PMC publication ID

3837907

19 August 2017

PubMed publication ID

24080664

1 reference

PMC publication ID

3837907