Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity (Q37336376)

19 August 2017

Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity (English)

1 reference

19 August 2017

Human coronavirus HKU1

0 references

Human coronavirus OC43

0 references

molecular biology

of

Human coronavirus HKU1

Human coronavirus OC43

1 reference

based on heuristic

inferred from abstract

1 reference

Christopher C. Stobart

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Sakshi Tomar

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Andrew D. Mesecar

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Mark R. Denison

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Nicole R Sexton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Havisha Munjal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Xiaotao Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Katrina L Molland

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

11 September 2013

1 reference

19 August 2017

8

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Virology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

12611-12618

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

Coronaviruses in bats from Mexico

13 June 2020

cites work

1 reference

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6 September 2017

1 reference

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6 September 2017

1 reference

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Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity

6 September 2017

1 reference

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Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses

6 September 2017

1 reference

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Profiling of substrate specificities of 3C-like proteases from group 1, 2a, 2b, and 3 coronaviruses

6 September 2017

1 reference

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Mutation of Asn28 Disrupts the Dimerization and Enzymatic Activity of SARS 3CL pro

6 September 2017

1 reference

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Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease.

6 September 2017

1 reference

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Coronavirus diversity, phylogeny and interspecies jumping

6 September 2017

1 reference

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Coronaviruses post-SARS: update on replication and pathogenesis

6 September 2017

1 reference

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Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro

6 September 2017

1 reference

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Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1

6 September 2017

1 reference

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Protein structure modeling with MODELLER

6 September 2017

1 reference

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A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing

6 September 2017

1 reference

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Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease

6 September 2017

1 reference

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Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

6 September 2017

1 reference

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Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations

6 September 2017

1 reference

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Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus

6 September 2017

1 reference

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Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing

6 September 2017

1 reference

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Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

6 September 2017

1 reference

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A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

6 September 2017

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Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction

6 September 2017

1 reference

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Long-range cooperative interactions modulate dimerization in SARS 3CLpro.

6 September 2017

1 reference

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Functional and genetic analysis of coronavirus replicase-transcriptase proteins

6 September 2017

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6 September 2017

1 reference

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

6 September 2017

1 reference

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

1 reference

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SARS-like virus in the Middle East: a truly bat-related coronavirus causing human diseases

28 September 2017

1 reference

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Increase of SARS-CoV 3CL peptidase activity due to macromolecular crowding effects in the milieu composition

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838113

Determinants of mouse hepatitis virus 3C-like proteinase activity.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838113

Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot

26 June 2018

1 reference

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The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase

26 June 2018

1 reference

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Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode

26 June 2018

1 reference

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The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838113

The substrate specificity of SARS coronavirus 3C-like proteinase

2 September 2018

1 reference

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Conservation of substrate specificities among coronavirus main proteases

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838113

Only one protomer is active in the dimer of SARS 3C-like proteinase

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24027335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.02050-13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027335%20AND%20SRC:MED&resulttype=core&format=json