Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells. (Q37349719)

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scientific article published on 18 August 2009

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English	Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.	scientific article published on 18 August 2009

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scholarly article

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5 February 2020

Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells (English)

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Walter J. Storkus

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Leonard M Neckers

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Mayumi Kawabe

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Maja Mandic

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Jennifer L Taylor

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Cecilia A Vasquez

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Amy K Wesa

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18 August 2009

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Cancer Research

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6995-7003

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5 February 2020

Enhancement in specific CD8+ T cell recognition of EphA2+ tumors in vitro and in vivo after treatment with ligand agonists

1 reference

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Expression of EphA2 is prognostic of disease-free interval and overall survival in surgically treated patients with renal cell carcinoma

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Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors

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The role of ephrins and Eph receptors in cancer

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Differential regulation of EphA2 in normal and malignant cells

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Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer

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Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

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Differential EphA2 epitope display on normal versus malignant cells

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Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts

1 reference

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E-cadherin regulates the function of the EphA2 receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19690146

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Identifiers

10.1158/0008-5472.CAN-08-4511

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

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