Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor (Q37352399)

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scientific article published on March 1996

Language	Label	Description	Also known as
English	Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor	scientific article published on March 1996

Statements

scholarly article

1 reference

Europe PubMed Central

19 August 2017

Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor (English)

1 reference

Europe PubMed Central

19 August 2017

1 reference

based on heuristic

inferred from title

author name string

G C Howard

1

1 reference

Europe PubMed Central

19 August 2017

U K Misra

2

1 reference

Europe PubMed Central

19 August 2017

D L DeCamp

3

1 reference

Europe PubMed Central

19 August 2017

S V Pizzo

4

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

1 March 1996

1 reference

Europe PubMed Central

19 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

19 August 2017

97

1 reference

Europe PubMed Central

19 August 2017

5

1 reference

Europe PubMed Central

19 August 2017

1193-1203

1 reference

Europe PubMed Central

19 August 2017

Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507171

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Receptor-recognized alpha 2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages

1 reference

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The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor

1 reference

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Recycling receptors: The round-trip itinerary of migrant membrane proteins

1 reference

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Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin

1 reference

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Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin.

1 reference

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Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

1 reference

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Receptor-mediated endocytosis: concepts emerging from the LDL receptor system

1 reference

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A conserved region in alpha-macroglobulins participates in binding to the mammalian alpha-macroglobulin receptor

1 reference

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Domain structure of human alpha 2-macroglobulin. Characterization of a receptor-binding domain obtained by digestion with papain

1 reference

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NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

1 reference

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39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

1 reference

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6 September 2017

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor

1 reference

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Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein

1 reference

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Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

1 reference

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A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein

1 reference

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alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions

1 reference

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Uptake and degradation of α2-macroglobulin-protease complexes in human cells in culture

1 reference

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Physical and chemical properties of human plasma β2-macroglobulin

1 reference

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6 September 2017

The electrophoretically ‘slow’ and ‘fast’ forms of the α2-macroglobulin molecule

1 reference

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Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages

1 reference

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Analysis of macrophage surface receptors. I. Binding of alpha-macroglobulin . protease complexes to rabbit alveolar macrophages

1 reference

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alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation

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The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins.

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Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431

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Receptor-mediated antigen delivery into macrophages. Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells

1 reference

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The relationship between low density lipoprotein-related protein/alpha 2-macroglobulin (alpha 2M) receptors and the newly described alpha 2M signaling receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507171

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Binding analysis of amino-terminal and carboxyl-terminal regions of the 39-kDa protein to the low density lipoprotein receptor-related protein.

1 reference

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Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure

1 reference

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The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

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Interactions between bovine -chymotrypsin and the protease inhibitors of human and dog serum in vitro.

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Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site

1 reference

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Binding of alpha 2-macroglobulin to hepatocytes: mechanism of in vivo clearance.

1 reference

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Binding of alpha 2-macroglobulin-thrombin complexes and methylamine-treated alpha 2-macroglobulin to human blood monocytes

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Recognition of chylomicron remnants and β-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver α2-macroglobulin-recognition site

1 reference

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Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor.

1 reference

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Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli.

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Heterogeneous lipoprotein (a) size isoforms differ by their interaction with the low density lipoprotein receptor and the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

1 reference

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Changes in the binding of "fast"-form .alpha.2-macroglobulin to 3T3-L1 cells after differentiation to adipocytes

1 reference

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Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin.

1 reference

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Characterization, size estimation and solubilization of alpha-macroglobulin complex receptors in liver membranes

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The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation

1 reference

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12 December 2020

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A monoclonal antibody to a neo-antigen on alpha 2-macroglobulin complexes inhibits receptor-mediated endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered clearance of human α2-macroglobulin complexes following reaction with cis-dichlorodiamineplatinum(II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell association and degradation of alpha 2-macroglobulin-trypsin complexes in hepatocytes and adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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based on heuristic

inferred from PubMed ID database lookup

Complexes of serum albumin and cis-dichlorodiammineplatinum (II). The role of cysteine 34 as a nucleophilic entering group and evidence for reaction between bound platinum and a second macromolecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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The primary structure of alpha 2-macroglobulin and localization of a Factor XIIIa cross-linking site

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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Characterization of receptors for alpha 2-macroglobulin-trypsin complex in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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The receptor-binding domain of human alpha 2-macroglobulin. Isolation after limited proteolysis with a bacterial proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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Evidence that the platinum-reactive methionyl residue of the alpha 2-macroglobulin receptor recognition site is not in the carboxyl-terminal receptor binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A

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Production of conformation-specific monoclonal antibodies against alpha 2 macroglobulin and their use for quantitation of total and transformed alpha 2 macroglobulin in human blood

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Evidence for a second alpha 2-macroglobulin receptor

1 reference

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Clinical and pharmacological studies with cis-diamminedichloroplatinum (II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8636430

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based on heuristic

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Study on the plasmatic elimination of the alpha2-macroglobulin-proteinase complexes

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Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs

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Intracellular polypeptide hormone receptors. Characterization of insulin binding sites in Golgi fractions from the liver of female rats

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Ligation of α2M Receptors with α2M‐Methylamine Stimulates the Activities of Phospholipase C, Phospholipase A2, and Protein Kinase C in Murine Peritoneal Macrophages

1 reference

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Identifiers

10.1172/JCI118533

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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