Assessing biological aging: the origin of deficit accumulation (Q37356978)

19 August 2017

Assessing biological aging: the origin of deficit accumulation (English)

1 reference

19 August 2017

3

Kenneth Rockwood

1 reference

19 August 2017

Arnold Mitnitski

1

1 reference

PMCID

3847281

19 August 2017

Xiaowei Song

series ordinal

2

1 reference

19 August 2017

17 July 2013

1 reference

19 August 2017

1 reference

19 August 2017

14

1 reference

19 August 2017

6

1 reference

19 August 2017

709-717

1 reference

Creative Commons Attribution 2.0 Generic

19 August 2017

start time

17 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s10522-013-9446-3

0 references

cites work

Healthy ageing, but what is health?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Recovery and survival from aging-associated diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Exploring the relationship between national economic indicators and relative fitness and frailty in middle-aged and older Europeans.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty in elderly people

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The role of DNA damage and repair in aging through the prism of Koch-like criteria.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Molecular regulation of telomerase activity in aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Constructing an index of physical fitness age for Japanese elderly based on 7-year longitudinal data: sex differences in estimated physical fitness age.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Transitions in frailty status in older adults in relation to mobility: a multistate modeling approach employing a deficit count.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Systems biology of ageing and longevity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Aging, frailty and age-related diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

MicroRNA-regulated protein-protein interaction networks: how could they help in searching for pro-longevity targets?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Protein homeostasis and aging: The importance of exquisite quality control

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Dynamics and heterogeneity in the process of human frailty and aging: evidence from the U.S. older adult population

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Mechanisms of dealing with DNA damage in terminally differentiated cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

A frailty index to predict the mortality risk in a population of senior Mexican adults.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Impact of exercise in community-dwelling older adults

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty and type of death among older adults in China: prospective cohort study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty and mortality among Chinese at advanced ages

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Wound repair and regeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Senescence, apoptosis or autophagy? When a damaged cell must decide its path--a mini-review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty in relation to the accumulation of deficits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Accelerated accumulation of health deficits as a characteristic of aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Stochastic model for analysis of longitudinal data on aging and mortality

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Health decline, aging and mortality: how are they related?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The quest for genetic determinants of human longevity: challenges and insights

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Modeling bursts and heavy tails in human dynamics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Irreversible processes at nonequilibrium steady states and Lyapounov functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The origin of bursts and heavy tails in human dynamics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Understanding the odd science of aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty, fitness and late-life mortality in relation to chronological and biological age

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Strategy for identifying biomarkers of aging in long-lived species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The network and the remodeling theories of aging: historical background and new perspectives

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The evolution of ageing and longevity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Is rate of skin wound healing associated with aging or longevity phenotype?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Operationalizing a frailty index from a standardized comprehensive geriatric assessment.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Where wealth matters more for health: the wealth-health gradient in 16 countries

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

A limit to frailty in very old, community-dwelling people: a secondary analysis of the Chinese longitudinal health and longevity study

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Trajectories of changes over twelve years in the health status of Canadians from late middle age.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Recovery rates reflect distance to a tipping point in a living system.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

A procedure for creating a frailty index based on deficit accumulation in aging mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Biogerontology: from here to where? The Lord Cohen Medal Lecture-2011.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty defined by deficit accumulation and geriatric medicine defined by frailty.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Complex systems: Foreseeing tipping points.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

The NetAge database: a compendium of networks for longevity, age-related diseases and associated processes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Effect of smoking on the accumulation of deficits, frailty and survival in older adults: a secondary analysis from the Canadian Study of Health and Aging.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Modeling the impact of sex on how exercise is associated with cognitive changes and death in older Canadians.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Public health significance of the frailty index.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Frailty index as a measure of biological age in a Chinese population.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

Continuous remodeling as a key to aging and survival: an interview with Claudio Franceschi. Interview by Suresh I S Rattan

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3847281

A Proof for the Queuing Formula:L= λW

2 September 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9446-3

OR FORUM—Little's Law as Viewed on Its 50th Anniversary

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9446-3

Long-Term Risks of Death and Institutionalization of Elderly People in Relation to Deficit Accumulation at Age 70

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9446-3

The impact of frailty and delirium on mortality in older inpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-013-9446-3

Autophagic activity and aging in human odontoblasts

21 January 2018

1 reference

12 December 2020

Biological aging research today: potential, peeves, and problems

1 reference

12 December 2020

Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality

1 reference

12 December 2020

General theory of mortality and aging

1 reference

12 December 2020

Limits to deficit accumulation in elderly people

1 reference

12 December 2020

Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity

1 reference

12 December 2020

Going from bad to worse: a stochastic model of transitions in deficit accumulation, in relation to mortality

1 reference

12 December 2020

Accumulation of deficits as a proxy measure of aging

1 reference

12 December 2020

New horizons in frailty: ageing and the deficit-scaling problem

1 reference

12 December 2020

Predictors of adverse outcomes on an acute geriatric rehabilitation ward

1 reference

12 December 2020

Immunological responses to pneumococcal vaccine in frail older people

1 reference

12 December 2020

How should we grade frailty in nursing home patients?

1 reference

12 December 2020

Evaluation of a frailty index based on a comprehensive geriatric assessment in a population based study of elderly Canadians

1 reference

12 December 2020

1 reference

12 December 2020

10.1007/S10522-013-9446-3

Identifiers

DOI

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

3847281