Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression (Q37363085)

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scientific article published on February 1997

Language	Label	Description	Also known as
English	Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression	scientific article published on February 1997

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression (English)

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Europe PubMed Central

19 August 2017

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multiple myeloma

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based on heuristic

inferred from title

Diane F. Jelinek

1

object named as

D F Jelinek

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Europe PubMed Central

19 August 2017

Renee C. Tschumper

5

object named as

R C Tschumper

1 reference

Europe PubMed Central

19 August 2017

author name string

K M Aagaard-Tillery

2

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Europe PubMed Central

19 August 2017

B K Arendt

3

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Europe PubMed Central

19 August 2017

T Arora

4

1 reference

Europe PubMed Central

19 August 2017

J J Westendorf

6

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Europe PubMed Central

19 August 2017

language of work or name

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publication date

1 February 1997

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Europe PubMed Central

19 August 2017

Journal of Clinical Investigation

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Europe PubMed Central

19 August 2017

99

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Europe PubMed Central

19 August 2017

447-456

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Europe PubMed Central

19 August 2017

3

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Europe PubMed Central

19 August 2017

describes a project that uses

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STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Interferon-gamma priming effects in the activation and deactivation of ISGF3 in K562 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Interleukin 1 signaling occurs exclusively via the type I receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Induction by interleukin-6 of interferon regulatory factor 1 (IRF-1) gene expression through the palindromic interferon response element pIRE and cell type-dependent control of IRF-1 binding to DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Cytokine therapeutics: lessons from interferon alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Interleukin-6 family of cytokines and gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Interferons and their actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Transcription factors induced by interferons alpha and gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Specific depletion of the B-cell population induced by aberrant expression of human interferon regulatory factor 1 gene in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Antitumour effects of interferons: past, present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Transcriptional regulation of interferon-stimulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Cytokine gene regulation: regulatory cis-elements and DNA binding factors involved in the interferon system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Interferon therapy in myelomatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

6 September 2017

Standard treatment of multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

14 September 2017

Interferon-alpha for induction and maintenance in multiple myeloma: results of two multicenter randomized trials and summary of other studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

14 September 2017

Regulation of the interferon system and cell growth by the IRF transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

14 September 2017

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

28 September 2017

Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

28 September 2017

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

28 September 2017

Interferon-alpha down-regulates the interleukin-6 receptor in a human multiple myeloma cell line, U266.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

28 September 2017

Interferon-alpha-2b downregulation of oncogenes H-ras, c-raf-2, c-kit, c-myc, c-myb and c-fos in ESKOL, a hairy cell leukemic line, results in temporal perturbation of signal transduction cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

28 September 2017

Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

Correlation between in vitro and in vivo sensitivity to human leucocyte interferon in patients with multiple myeloma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

The in vitro effect of leucocyte alpha-interferon on human myeloma cells in a semisolid agar culture system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

The effect of alpha and gamma-interferon on proliferation and production of IgE and beta 2-microglobulin in the human myeloma cell line U-266 and in an alpha-interferon resistant U-266 subline.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

IFN-alpha induces autocrine production of IL-6 in myeloma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

Plasma cell leukaemia with alpha-interferon therapy in myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

26 June 2018

Interleukin-6 activates and regulates transcription factors of the interferon regulatory factor family in M1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

2 September 2018

Murine T helper cell-2 lymphocytes express type I and type II IL-1 receptors, but only the type I receptor mediates costimulatory activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507818

2 September 2018

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant interferon-gamma inhibits the in vitro proliferation of human myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon exerts a cytotoxic effect on primary human myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of aggressive plasma cell leukaemia under interferon-alpha therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized trial of interferon maintenance in multiple myeloma: a study of the National Cancer Institute of Canada Clinical Trials Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Janus protein tyrosine kinase family and its role in cytokine signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-Interferon in multiple myeloma: inhibition of interleukin-6 (IL-6)-dependent myeloma cell growth and downregulation of IL-6-receptor expression in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9022078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119179

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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