Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans (Q37363157)

19 August 2017

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans (English)

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19 August 2017

Alison H Harrill

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David W. Threadgill

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David W Threadgill

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Raymond Tennant

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19 August 2017

Paul B Watkins

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19 August 2017

Stephen Su

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19 August 2017

Pamela K Ross

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19 August 2017

David E Harbourt

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19 August 2017

Ioannis M Stylianou

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19 August 2017

Gary A Boorman

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19 August 2017

Mark W Russo

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19 August 2017

Richard S Sackler

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19 August 2017

Stephen C Harris

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19 August 2017

Philip C Smith

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19 August 2017

Molly Bogue

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19 August 2017

Kenneth Paigen

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19 August 2017

Christopher Harris

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19 August 2017

Tanupriya Contractor

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19 August 2017

Timothy Wiltshire

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19 August 2017

Ivan Rusyn

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19 August 2017

5 May 2009

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19 August 2017

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19 August 2017

1507-1515

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19 August 2017

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Toxicology. Transforming environmental health protection

19 August 2017

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Pharmacogenetics: using DNA to optimize drug therapy

6 September 2017

1 reference

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The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

The clinical role of genetic polymorphisms in drug-metabolizing enzymes

6 September 2017

1 reference

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Retrospective analysis of transient elevations in alanine aminotransferase during long-term treatment with acetaminophen in osteoarthritis clinical trials

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Upregulation of calpastatin in regenerating and developing rat liver: role in resistance against hepatotoxicity

6 September 2017

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Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

6 September 2017

1 reference

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Comparative analysis of haplotype association mapping algorithms

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Idiosyncratic drug hepatotoxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

6 September 2017

1 reference

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Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice

6 September 2017

1 reference

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Acute Liver Failure in the United States

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

One Hundred Years of Mouse Genetics: An Intellectual History. II. The Molecular Revolution (1981-2002)

6 September 2017

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Genetics of gene expression surveyed in maize, mouse and man

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

6 September 2017

A mouse phenome project

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Drug-induced liver diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Genealogies of mouse inbred strains

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Cytokines and toxicity in acetaminophen overdose

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Critical role of CD44 in hepatotoxin-mediated liver injury

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions

2 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Pharmacogenomic biomarkers for prediction of severe adverse drug reactions

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Acetaminophen toxicity: changing perceptions on a social/medical issue

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Neutrophil depletion protects against murine acetaminophen hepatotoxicity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

CD44 disruption prevents degeneration of the capillary network in obstructive nephropathy via reduction of TGF-beta1-induced apoptosis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Hepatic gene expression changes throughout the day in the Fischer rat: implications for toxicogenomic experiments.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Animal models of idiosyncratic drug reactions.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752130

How relevant are neutrophils for acetaminophen hepatotoxicity?

2 September 2018

1 reference

12 December 2020

International Federation of Clinical Chemistry (IFCC) Scientific Committee, Analytical Section: approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes. Part 3. IFCC method for alanine aminotransferas

1 reference

12 December 2020

The Mouse Phenome Project

1 reference

12 December 2020

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

1 reference

12 December 2020

Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.090241.108

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19 August 2017

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19 August 2017

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