Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture. (Q37375061)

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English	Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.	scientific article

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7 November 2019

Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture (English)

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7 November 2019

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7 November 2019

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W H Busby

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C E Smith

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7 November 2019

J B Clarke

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A J Garmong

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7 November 2019

G D Horwitz

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C Rees

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7 November 2019

D R Clemmons

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1 November 1997

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7 November 2019

Journal of Clinical Investigation

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7 November 2019

2596-2605

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7 November 2019

Insulin-like growth factor-I (IGF-I) regulates IGF-binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells

1 reference

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Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I.

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Variables controlling somatomedin production by cultured human fibroblasts

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Exposure to platelet-derived growth factor modulates the porcine aortic smooth muscle cell response to somatomedin-C.

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26 June 2018

Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.

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Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF I-induced stimulation of osteoblasts: control of IGF signalling to bone cells by IGFBP-3-specific proteolysis?

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26 June 2018

Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone

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Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): comparison of its structural and functional properties with IGFBP-1

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Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II

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Substitution of specific amino acids in insulin-like growth factor (IGF) binding protein 5 alters heparin binding and its change in affinity for IGF-I response to heparin

1 reference

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Binding of insulin-like growth factor (IGF) I or II to IGF-binding protein-2 enables it to bind to heparin and extracellular matrix

1 reference

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Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts

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1 reference

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12 December 2020

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In vivo proliferation of rat vascular smooth muscle in relation to diabetes mellitus insulin-like growth factor I and insulin

1 reference

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12 December 2020

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Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion

1 reference

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12 December 2020

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1 reference

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Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cells

1 reference

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12 December 2020

based on heuristic

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human fibroblasts secrete a serine protease that cleaves insulin-like growth factor-binding protein-5

1 reference

https://pubmed.ncbi.nlm.nih.gov/9366575

12 December 2020

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Glycosaminoglycans inhibit degradation of insulin-like growth factor-binding protein-5

1 reference

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1 reference

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Identifiers

10.1172/JCI119803

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7 November 2019

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7 November 2019

1 reference

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7 November 2019

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