Matrix metalloproteinases and their multiple roles in neurodegenerative diseases (Q37375110)

20 August 2017

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title

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases (English)

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20 August 2017

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Gary A Rosenberg

1

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PubMed ID

19161911

20 August 2017

language of work or name

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1 February 2009

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20 August 2017

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20 August 2017

8

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20 August 2017

205-216

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20 August 2017

2

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The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases.

20 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Multiple roles for MMPs and TIMPs in cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Metalloproteinases: mediators of pathology and regeneration in the CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Strategies for MMP inhibition in cancer: innovations for the post-trial era.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Remarkable roles of proteolysis on and beyond the cell surface

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Metalloproteinase inhibitors: biological actions and therapeutic opportunities.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Processing of tumour necrosis factor-α precursor by metalloproteinases

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Tissue inhibitors of metalloproteinases: evolution, structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Tissue inhibitor of metalloproteinase-3 is associated with neuronal death in reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Differential regulation of tissue inhibitor of metalloproteinase mRNA expression in response to intracranial injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Regulation of tissue inhibitor of metalloproteinase-3 (Timp-3) mRNA expression during rat CNS development

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Differential expression of tissue inhibitor of metalloproteinases-3 in cultured astrocytes and neurons regulates the activation of matrix metalloproteinase-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinases degrade myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Mechanisms, challenges and opportunities in stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinases increase very early during experimental focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Blood-brain barrier disruption by stromelysin-1 facilitates neutrophil infiltration in neuroinflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase expression during experimental autoimmune neuritis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Leukocyte Gelatinase B Cleavage Releases Encephalitogens from Human Myelin Basic Protein

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Modern concept of vascular cognitive impairment

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

White matter damage is associated with matrix metalloproteinases in vascular dementia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Binswanger's disease--revisited

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Silent brain infarcts and the risk of dementia and cognitive decline.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Pathogenesis of Binswanger chronic progressive subcortical encephalopathy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Glial activation and white matter changes in the rat brain induced by chronic cerebral hypoperfusion: an immunohistochemical study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Chronic cerebral hypoperfusion induces MMP-2 but not MMP-9 expression in the microglia and vascular endothelium of white matter.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Transcriptional responses to intermittent hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Intracellular amyloid-beta in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

The APP family of proteins: similarities and differences

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Association of matrix metalloproteinase 3 promoter genotype with disease outcome in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with carotid artery stenosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Impact of the matrix metalloproteinase MMP-3 on dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase 3 haplotypes and dementia and Alzheimer's disease. The Rotterdam Study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Abnormal expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in brain arteriovenous malformations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Doxycycline suppresses cerebral matrix metalloproteinase-9 and angiogenesis induced by focal hyperstimulation of vascular endothelial growth factor in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Angiogenic recruitment of pericytes from bone marrow after stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

In pneumococcal meningitis a novel water-soluble inhibitor of matrix metalloproteinases and TNF-alpha converting enzyme attenuates seizures and injury of the cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Effective combination of minocycline and interferon-beta in a model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Recent advances in MMP inhibitor design

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood-brain barrier opening in rodents: Differences in response based on strains and solvents

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2809%2970016-X

7 January 2021

10.1016/S1474-4422(09)70016-X

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19161911