Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo (Q37377754)

20 August 2017

Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo (English)

1 reference

20 August 2017

Yekaterina B Khotskaya

1

1 reference

20 August 2017

Yuemeng Dai

2

1 reference

20 August 2017

Joseph P Ritchie

3

1 reference

20 August 2017

Veronica MacLeod

4

1 reference

20 August 2017

Yang Yang

5

1 reference

20 August 2017

Kurt Zinn

6

1 reference

20 August 2017

Ralph D Sanderson

7

1 reference

20 August 2017

language of work or name

English

0 references

publication date

13 July 2009

1 reference

Journal of Biological Chemistry

20 August 2017

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20 August 2017

284

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20 August 2017

26085-26095

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20 August 2017

38

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describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2758008/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma

6 September 2017

1 reference

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Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment

6 September 2017

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Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells

6 September 2017

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Syndecan-1: a dynamic regulator of the myeloma microenvironment

6 September 2017

1 reference

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Molecular and cellular mechanisms of syndecans in tissue injury and inflammation

6 September 2017

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Extravasation and homing mechanisms in multiple myeloma

6 September 2017

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The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy

6 September 2017

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Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions

6 September 2017

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Synopsis of a roundtable on validating novel therapeutics for multiple myeloma

6 September 2017

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Enhancement of clonogenicity of human multiple myeloma by dendritic cells

6 September 2017

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Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma

6 September 2017

1 reference

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Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma

6 September 2017

1 reference

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HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo

6 September 2017

1 reference

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The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells

6 September 2017

1 reference

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Characterization of clonogenic multiple myeloma cells

6 September 2017

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Synopsis of a research roundtable presented on cell signaling in myeloma: regulation of growth and apoptosis--opportunities for new drug discovery

6 September 2017

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Soluble syndecan-1 promotes growth of myeloma tumors in vivo

6 September 2017

1 reference

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High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity

6 September 2017

1 reference

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Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis

6 September 2017

1 reference

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Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody

6 September 2017

1 reference

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Molecular cloning of syndecan, an integral membrane proteoglycan

6 September 2017

1 reference

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Bone marrow stroma confers resistance to Apo2 ligand/TRAIL in multiple myeloma in part by regulating c-FLIP.

6 September 2017

1 reference

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Induction of syndecan-1 expression in stromal fibroblasts promotes proliferation of human breast cancer cells

14 September 2017

1 reference

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Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins

14 September 2017

1 reference

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A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758008

Role of the bone marrow microenvironment in multiple myeloma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758008

Syndecan-1 (CD138) immunoreactivity in bone marrow biopsies of multiple myeloma: shed syndecan-1 accumulates in fibrotic regions.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758008

Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparin-binding proteins.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758008

The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2758008

Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.018473

Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice

21 January 2018

1 reference

12 December 2020

A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1

1 reference

12 December 2020

Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations

1 reference

12 December 2020

The proliferative potential of myeloma plasma cells manifest in the SCID-hu host

1 reference

12 December 2020

Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis

1 reference

12 December 2020

Detection of myeloma cells in the peripheral blood by flow cytometry

1 reference

12 December 2020

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.018473

1 reference

20 August 2017

1 reference

20 August 2017

1 reference