Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis (Q37384053)

20 August 2017

Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. (English)

1 reference

20 August 2017

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Kevin W Williams

8

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author name string

Eric D Berglund

1

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20 August 2017

Chen Liu

2

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20 August 2017

Jong-Woo Sohn

3

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20 August 2017

Tiemin Liu

4

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20 August 2017

Mi Hwa Kim

5

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20 August 2017

Charlotte E Lee

6

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20 August 2017

Claudia R Vianna

7

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20 August 2017

Yong Xu

9

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20 August 2017

Joel K Elmquist

10

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20 August 2017

language of work or name

English

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publication date

1 November 2013

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Journal of Clinical Investigation

20 August 2017

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20 August 2017

123

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20 August 2017

12

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20 August 2017

5061-5070

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Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons

20 August 2017

1 reference

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Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

6 September 2017

1 reference

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What is the prognosis for new centrally-acting anti-obesity drugs?

6 September 2017

1 reference

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Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

6 September 2017

1 reference

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Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

6 September 2017

1 reference

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Serotonergic anti-obesity agents: past experience and future prospects

6 September 2017

1 reference

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Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels

6 September 2017

1 reference

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The use of serotonergic drugs to treat obesity--is there any hope?

6 September 2017

1 reference

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Role of central serotonin and melanocortin systems in the control of energy balance

6 September 2017

1 reference

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A serotonin and melanocortin circuit mediates D-fenfluramine anorexia

6 September 2017

1 reference

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Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects

6 September 2017

1 reference

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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility

6 September 2017

1 reference

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Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons

6 September 2017

1 reference

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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

6 September 2017

1 reference

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Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass

6 September 2017

1 reference

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Pharmacological targeting of the serotonergic system for the treatment of obesity

6 September 2017

1 reference

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Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors

6 September 2017

1 reference

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Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways

6 September 2017

1 reference

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Serotonin and energy balance: molecular mechanisms and implications for type 2 diabetes

6 September 2017

1 reference

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Glucagon and regulation of glucose metabolism

6 September 2017

1 reference

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Valvular heart disease associated with fenfluramine-phentermine

6 September 2017

1 reference

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Ligand-activated site-specific recombination in mice

6 September 2017

1 reference

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Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

6 September 2017

1 reference

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5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system

6 September 2017

1 reference

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Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

6 September 2017

1 reference

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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Impact of lack of suppression of glucagon on glucose tolerance in humans

26 June 2018

1 reference

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Effect of d-fenfluramine on basal glucose turnover and fat-feeding-induced insulin resistance in rats.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Serotonin release in lateral and medial hypothalamus during feeding and its anticipation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

The FDA's assessment of two drugs for chronic weight management

26 June 2018

1 reference

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NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.

2 September 2018

1 reference

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Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Measurement of size and turnover rate of body glucose pool by the isotope dilution method

2 September 2018

1 reference

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Activation of central melanocortin pathways by fenfluramine

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

The central melanocortin system can directly regulate serum insulin levels.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes.

2 September 2018

1 reference

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Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859401

Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

3 December 2018

1 reference

12 December 2020

Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus

1 reference

12 December 2020

Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry

1 reference

12 December 2020

Hyperglycemic properties of serotonin receptor antagonists

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12 December 2020

Identifiers

DOI

10.1172/JCI70338

1 reference

20 August 2017

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20 August 2017

1 reference