Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice (Q37387075)

20 August 2017

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title

Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice (English)

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20 August 2017

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Toshio Takeda

1

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20 August 2017

publication date

7 February 2009

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20 August 2017

published in

Neurochemical Research

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20 August 2017

volume

34

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20 August 2017

issue

4

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20 August 2017

page(s)

639-659

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Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence.

20 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Molecular genetic characterization of the senescence-accelerated mouse (SAM) strains.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Early onset of age-related impairment of aversive and appetitive learning in the SAM-P/8 mouse

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Analysis of the expression of endogenous murine leukemia viruses in the brains of senescence-accelerated mice (SAMP8) and the relationship between expression and brain histopathology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Permeability of the blood-brain barrier to albumin and insulin in the young and aged SAMP8 mouse

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Epigenetic mechanisms in memory formation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11064-009-9922-Y

Senescence-accelerated mouse (SAM): Age-related reduced anxiety-like behavior in the SAM-P/8 strain

21 January 2018

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12 December 2020

Periodic acid-Schiff (PAS)-positive, granular structures increase in the brain of senescence accelerated mouse (SAM).

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12 December 2020

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12 December 2020

Grading score system: a method for evaluation of the degree of senescence in senescence accelerated mouse (SAM).

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12 December 2020

Expression of neurotrophin genes in the brain of senescence-accelerated mouse (SAM) during postnatal development

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12 December 2020

Learning and memory in the SAMP8 mouse

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12 December 2020

Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (Tempol).

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12 December 2020

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12 December 2020

Purification and structural analysis of hippocampal cholinergic neurostimulating peptide

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12 December 2020

Spontaneous and artificial lesions of magnocellular reticular formation of brainstem deteriorate avoidance learning in senescence-accelerated mouse SAM.

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12 December 2020

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12 December 2020

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12 December 2020

Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice

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12 December 2020

Increased expression of hippocampal cholinergic neurostimulating peptide-related components and their messenger RNAs in the hippocampus of aged senescence-accelerated mice

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12 December 2020

[Loss of dendritic spines in hippocampal CA1 pyramidal cells in senescence accelerated mouse (SAM)--a quantitative Golgi study]

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12 December 2020

The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease

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12 December 2020

Hyperexcitability of amygdala neurons of senescence-accelerated mouse revealed by electrical and optical recordings in an in vitro slice preparation

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12 December 2020

Titers of murine leukemia virus are higher in brains of SAMP8 than SAMR1 mice

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12 December 2020

Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein

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12 December 2020

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12 December 2020

Pathobiology of the senescence-accelerated mouse (SAM).

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12 December 2020

The spin-trap N-tert-alpha-phenyl-butylnitrone prolongs the life span of the senescence accelerated mouse

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12 December 2020

Brain lipid hydroperoxide level increases in senescence-accelerated mice at an early age.

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12 December 2020

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12 December 2020

Inbred SAM-P/10 as a Mouse Model of Spontaneous, Inherited Brain Atrophy

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12 December 2020

Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouse

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12 December 2020

Cell death in the Purkinje cells of the cerebellum of senescence accelerated mouse (SAMP(8)).

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12 December 2020

Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse

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12 December 2020

Genetics of gene expression and its effect on disease

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12 December 2020

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12 December 2020

An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice; an age-associated neurodegeneration animal model

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12 December 2020

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12 December 2020

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

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12 December 2020

Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice

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12 December 2020

D-serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8.

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12 December 2020

Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain

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12 December 2020

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12 December 2020

Limbic structures are prone to age-related impairments in proteasome activity and neuronal ubiquitinated inclusions in SAMP10 mouse: a model of cerebral degeneration

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12 December 2020

Learning deficiency and alterations in acetylcholine receptors and protein kinase C in the brain of senescence-accelerated mouse (SAM)-P10.

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12 December 2020

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12 December 2020

Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease

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12 December 2020

Apical vulnerability to dendritic retraction in prefrontal neurones of ageing SAMP10 mouse: a model of cerebral degeneration

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12 December 2020

Attenuating effect of diazepam on stress-induced increases in noradrenaline turnover in specific brain regions of rats: antagonism by Ro 15-1788.

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12 December 2020

Increased expression of cathepsins E and D in reactive microglial cells associated with spongiform degeneration in the brain stem of senescence-accelerated mouse.

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12 December 2020

Senescence-accelerated mouse (SAM): a biogerontological resource in aging research

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12 December 2020

Mechanisms of aging in senescence-accelerated mice

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12 December 2020

Ligand-binding characteristics of [3H]QNB, [3H]prazosin, [3H]rauwolscine, [3H]TCP and [3H]nitrendipine to cerebral cortical and hippocampal membranes of senescence accelerated mouse.

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12 December 2020

Immunocytochemical study of catecholaminergic neurons in the senescence-accelerated mouse (SAM-P8) brain

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12 December 2020

Impairment of CREB phosphorylation in the hippocampal CA1 region of the senescence-accelerated mouse (SAM) P8.

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12 December 2020

Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence-accelerated mice.

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12 December 2020

Murine leukemia virus in organs of senescence-prone and -resistant mouse strains

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12 December 2020

Mitochondrial dysfunction in the senescence accelerated mouse (SAM).

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12 December 2020

Variations in DNA elucidate molecular networks that cause disease

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12 December 2020

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12 December 2020

Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone

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12 December 2020

Cholinergic deficits in the septal-hippocampal pathway of the SAM-P/8 senescence accelerated mouse

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12 December 2020

Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM).

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12 December 2020

Identification of age-dependent changes in expression of senescence-accelerated mouse (SAMP8) hippocampal proteins by expression array analysis.

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12 December 2020

Recovery of learning and memory is associated with chromatin remodelling

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12 December 2020

Brain stem reticular formation neuronal correlates of stimulus significance and behavior during discriminative avoidance conditioning in rabbits

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12 December 2020

Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse

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12 December 2020

Early appearance of abnormality of microperoxisomal enzymes in the cerebral cortex of senescence-accelerated mouse

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12 December 2020

Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10.

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12 December 2020

Sphingomyelinase activity is enhanced in cerebral cortex of senescence-accelerated mouse-P/10 with advancing age.

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12 December 2020

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice

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12 December 2020

Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence accelerated mouse (SAM)-P10.

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12 December 2020

Defects of immune cells in the senescence-accelerated mouse: a model for learning and memory deficits in the aged

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12 December 2020

Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging.

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12 December 2020

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12 December 2020

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12 December 2020

A new murine model of accelerated senescence

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12 December 2020

Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task.

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12 December 2020

Elevated oxidative stress in the brain of senescence-accelerated mice at 5 months of age.

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12 December 2020

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12 December 2020

Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8.

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12 December 2020

Behavioral assessment of the senescence-accelerated mouse (SAM P8 and R1).

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12 December 2020

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12 December 2020

Early and transient increase in oxidative stress in the cerebral cortex of senescence-accelerated mouse

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12 December 2020

Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice

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12 December 2020

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12 December 2020

Increased permeability of blood–brain barrier on the hippocampus of a murine model of senescence

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12 December 2020

Alzheimer's disease and the cerebellum: a morphologic study on neuronal and glial changes

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12 December 2020

Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice

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12 December 2020

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12 December 2020

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12 December 2020

Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory

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12 December 2020

Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain

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12 December 2020

Alterations in acetylcholine, NMDA, benzodiazepine receptors and protein kinase C in the brain of the senescence-accelerated mouse: an animal model useful for studies on cognitive enhancers.

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12 December 2020

Bcl-2-linked apoptosis due to increase in NO synthase in brain of SAMP10.

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12 December 2020

Colocalization of prolyl endopeptidase and amyloid beta-peptide in brains of senescence-accelerated mouse

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12 December 2020

Differential gene expression profiles in the hippocampus of senescence-accelerated mouse.

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12 December 2020

Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse

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12 December 2020

Differential expression of HCNP-related antigens in hippocampus in senescence-accelerated mice

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12 December 2020

Biochemical changes related to aging in the senescence-accelerated mouse

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12 December 2020

A simple and reliable conflict procedure for testing anti-anxiety agents

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12 December 2020

Comparison of thiol redox state of mitochondria and homogenates of various tissues between two strains of mice with different longevities

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12 December 2020

Effect of age on calcium-dependent proteins in hippocampus of senescence-accelerated mice

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12 December 2020

Age-associated changes in superoxide dismutase activity, thiobarbituric acid reactivity and reduced glutathione level in the brain and liver in senescence accelerated mice (SAM): a comparison with ddY mice

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12 December 2020

Immunocytochemical evaluation of the blood-brain barrier to endogenous albumin in the olfactory bulb and pons of senescence-accelerated mice (SAM).

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12 December 2020

Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis

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12 December 2020

Alterations in calcium antagonist receptors and calcium content in senescent brain and attenuation by nimodipine and nicardipine

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12 December 2020

Deficiencies of hippocampal Zn and ZnT3 accelerate brain aging of Rat.

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12 December 2020

Modulation of voltage-gated Ca2+ current by 4-hydroxynonenal in dentate granule cells

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12 December 2020

Neuronal nuclear DNA fragmentation in the aged canine brain: apoptosis or nuclear DNA fragility?

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12 December 2020

Spontaneous spongy degeneration of the brain stem in SAM-P/8 mice, a newly developed memory-deficient strain.

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12 December 2020

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12 December 2020

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12 December 2020

Localization of atrophy-prone areas in the aging mouse brain: comparison between the brain atrophy model SAM-P/10 and the normal control SAM-R/1.

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12 December 2020

10.1007/S11064-009-9922-Y

Identifiers

DOI

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20 August 2017

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