Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists. (Q37391072)

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scientific article published on August 1996

Language	Label	Description	Also known as
English	Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.	scientific article published on August 1996

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8799186%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists (English)

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Europe PubMed Central

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19 October 2019

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Isabella Saggio

5

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19 October 2019

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A Di Marco

1

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19 October 2019

I Gloaguen

2

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19 October 2019

R Graziani

3

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19 October 2019

G Paonessa

4

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19 October 2019

K R Hudson

6

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19 October 2019

R Laufer

7

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19 October 2019

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publication date

1 August 1996

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19 October 2019

Proceedings of the National Academy of Sciences of the United States of America

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19 October 2019

93

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19 October 2019

17

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19 October 2019

9247-9252

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PMC publication ID

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19 October 2019

Hematopoietin sub-family classification based on size, gene organization and sequence homology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

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6 September 2017

The stoichiometry of growth hormone-binding protein complexes in human plasma: comparison with cell surface receptors

1 reference

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6 September 2017

The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

1 reference

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6 September 2017

Ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Functional phage display of ciliary neurotrophic factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Nonradioactive receptor binding assay for ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Interleukin-6 family of cytokines and gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Human ciliary neurotrophic factor: a structure-function analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

D1 cap region involved in the receptor recognition and neural cell survival activity of human ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

Neuropoietic cytokines in the hematopoietic fold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

6 September 2017

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

14 September 2017

A simple method for site-directed mutagenesis using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

14 September 2017

Rational design of a receptor super-antagonist of human interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

28 September 2017

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

28 September 2017

Coordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP, and leukemia inhibitory factor/ciliary neurotrophic factor signaling pathways in a murine septa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

28 September 2017

Development of a human interleukin-6 receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

26 June 2018

Recombinant human CNTF receptor alpha: production, binding stoichiometry, and characterization of its activity as a diffusible factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

26 June 2018

Immortalized young adult neurons from the septal region: generation and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

26 June 2018

Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons

1 reference

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26 June 2018

Rational design of potent antagonists to the human growth hormone receptor

1 reference

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26 June 2018

In vitro binding of ciliary neurotrophic factor to its receptors: evidence for the formation of an IL-6-type hexameric complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=38627

2 September 2018

Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells

1 reference

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3 December 2018

Reconstitution of the response to leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the receptor binding sites of human leukemia inhibitory factor and creation of antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exchange of a single amino acid interconverts the specific activity and gel mobility of human and rat ciliary neurotrophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential function of LIF receptor in motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of a Composite Binding Site for gp130 in Human Interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/8799186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.17.9247

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Europe PubMed Central

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19 October 2019

1996PNAS...93.9247D

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19 October 2019

PubMed publication ID

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Europe PubMed Central

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19 October 2019

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