Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin (Q37400545)

20 August 2017

Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin (English)

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20 August 2017

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S Bafna

1

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20 August 2017

S Kaur

series ordinal

2

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20 August 2017

N Momi

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3

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20 August 2017

S K Batra

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4

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20 August 2017

language of work or name

English

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publication date

8 September 2009

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British Journal of Cancer

20 August 2017

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20 August 2017

101

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20 August 2017

7

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20 August 2017

1155-1161

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6605285

20 August 2017

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cites work

The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms

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MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.

6 September 2017

1 reference

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MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells

6 September 2017

1 reference

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Targeting HER proteins in cancer therapy and the role of the non-target HER3.

6 September 2017

1 reference

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Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage

6 September 2017

1 reference

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BCL2 family of apoptosis-related genes: functions and clinical implications in cancer

6 September 2017

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Survivin: a protein with dual roles in mitosis and apoptosis

6 September 2017

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A review of systemic therapy for advanced pancreatic cancer

6 September 2017

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The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts

6 September 2017

1 reference

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Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis.

6 September 2017

1 reference

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Gastrointestinal cancers in Europe

6 September 2017

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Pancreatic cancer biology and genetics

6 September 2017

1 reference

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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

6 September 2017

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

6 September 2017

1 reference

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MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins.

6 September 2017

1 reference

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Epidermal growth factor protects prostate cancer cells from apoptosis by inducing BAD phosphorylation via redundant signaling pathways

14 September 2017

1 reference

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Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

Novel therapies for pancreatic adenocarcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

Concurrent chemoradiotherapy with gemcitabine and cisplatin for pancreatic cancer: from the laboratory to the clinic

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768097

2 September 2018

Identifiers

DOI

10.1038/SJ.BJC.6605285

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20 August 2017

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20 August 2017

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