Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence (Q37402528)

20 August 2017

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title

Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence (English)

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20 August 2017

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Koji Tomobe

1

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PubMed ID

19247832

20 August 2017

Yasuyuki Nomura

series ordinal

2

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20 August 2017

27 February 2009

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20 August 2017

Neurochemical Research

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20 August 2017

34

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20 August 2017

4

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20 August 2017

660-669

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https://scigraph.springernature.com/pub.10.1007/s11064-009-9923-x

20 August 2017

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https://api.crossref.org/works/10.1007%2FS11064-009-9923-X

Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS11064-009-9923-X

Molecular genetic characterization of the senescence-accelerated mouse (SAM) strains.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS11064-009-9923-X

Periodic acid-Schiff (PAS)-positive, granular structures increase in the brain of senescence accelerated mouse (SAM).

21 January 2018

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12 December 2020

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12 December 2020

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

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12 December 2020

Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria.

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12 December 2020

Oxidative stress and mitochondrial function with aging--the effects of calorie restriction

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12 December 2020

Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex I and oxidative DNA damage in rat brain

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12 December 2020

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

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12 December 2020

Direct evidence for biphasic cAMP responsive element-binding protein phosphorylation during long-term potentiation in the rat dentate gyrus in vivo.

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12 December 2020

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12 December 2020

Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice.

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12 December 2020

[Loss of dendritic spines in hippocampal CA1 pyramidal cells in senescence accelerated mouse (SAM)--a quantitative Golgi study]

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12 December 2020

A higher oxidative status accelerates senescence and aggravates age-dependent disorders in SAMP strains of mice

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12 December 2020

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

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12 December 2020

Modified hippocampal long-term potentiation in PKCγ-mutant mice

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12 December 2020

Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus.

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12 December 2020

The spin-trap N-tert-alpha-phenyl-butylnitrone prolongs the life span of the senescence accelerated mouse

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12 December 2020

Brain lipid hydroperoxide level increases in senescence-accelerated mice at an early age.

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12 December 2020

Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction.

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12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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12 December 2020

Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouse

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12 December 2020

Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging

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12 December 2020

Calorie restriction and aging: review of the literature and implications for studies in humans

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12 December 2020

Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse.

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12 December 2020

An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice; an age-associated neurodegeneration animal model.

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12 December 2020

Effects of age and dietary restriction on lifespan and oxidative stress of SAMP8 mice with learning and memory impairments.

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12 December 2020

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12 December 2020

Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart

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12 December 2020

Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats

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12 December 2020

Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls.

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12 December 2020

Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice.

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12 December 2020

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12 December 2020

Genetic typing of the senescence-accelerated mouse (SAM) strains with microsatellite markers.

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12 December 2020

Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice.

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12 December 2020

Immediate early gene transcription and synaptic modulation

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12 December 2020

Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement

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12 December 2020

Senescence-accelerated mouse. Neurochemical studies on aging.

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12 December 2020

Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density

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12 December 2020

Oxidative Damage to Behavior During Aging

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12 December 2020

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

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12 December 2020

Mechanisms of aging in senescence-accelerated mice

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12 December 2020

Impairment of CREB phosphorylation in the hippocampal CA1 region of the senescence-accelerated mouse (SAM) P8.

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12 December 2020

Mitochondrial dysfunction in the senescence accelerated mouse (SAM).

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12 December 2020

Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone

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12 December 2020

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

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12 December 2020

Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM).

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12 December 2020

Hormonal regulation of hippocampal spine synapse density involves subcortical mediation

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12 December 2020

Influence of diet on survival of mice

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12 December 2020

Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse

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12 December 2020

Early appearance of abnormality of microperoxisomal enzymes in the cerebral cortex of senescence-accelerated mouse.

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12 December 2020

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

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12 December 2020

Para/autocrine regulation of estrogen receptors in hippocampal neurons

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12 December 2020

Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig

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12 December 2020

Effects of age and dietary restriction on animal model SAMP8 mice with learning and memory impairments.

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12 December 2020

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice

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12 December 2020

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12 December 2020

Calorie restriction in obesity: prevention of kidney disease in rodents

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12 December 2020

Subcellular localization of estrogen receptor beta in mouse hippocampus

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12 December 2020

Elevated oxidative stress in the brain of senescence-accelerated mice at 5 months of age.

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12 December 2020

Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E.

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12 December 2020

Genetic characterization of senescence-accelerated mouse (SAM).

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12 December 2020

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12 December 2020

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12 December 2020

Forced swimming evokes a biphasic response in CREB phosphorylation in extrahypothalamic limbic and neocortical brain structures in the rat.

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12 December 2020

Sex differences and opposite effects of stress on dendritic spine density in the male versus female hippocampus.

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12 December 2020

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12 December 2020

Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice

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12 December 2020

Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment

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12 December 2020

Increased anxiety and synaptic plasticity in estrogen receptor beta -deficient mice.

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12 December 2020

Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice

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12 December 2020

Two neurons mediate diet-restriction-induced longevity in C. elegans

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12 December 2020

Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory.

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12 December 2020

Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease

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12 December 2020

Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain.

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12 December 2020

Alterations in acetylcholine, NMDA, benzodiazepine receptors and protein kinase C in the brain of the senescence-accelerated mouse: an animal model useful for studies on cognitive enhancers.

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12 December 2020

LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite.

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12 December 2020

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans

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12 December 2020

Differential gene expression profiles in the hippocampus of senescence-accelerated mouse.

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12 December 2020

Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain.

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12 December 2020

Antioxidative activity and ameliorative effects of memory impairment of sulfur-containing compounds in Allium species.

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12 December 2020

Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo.

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12 December 2020

Biochemical changes related to aging in the senescence-accelerated mouse

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12 December 2020

Synaptic plasticity and dynamic modulation of the postsynaptic membrane

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12 December 2020

Genetic analysis of learning and memory deficits in senescence-accelerated mouse (SAM).

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12 December 2020

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

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12 December 2020

Effect of age on calcium-dependent proteins in hippocampus of senescence-accelerated mice.

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12 December 2020

Distribution and hormone regulation of estrogen receptor immunoreactive cells in the hippocampus of male and female rats.

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12 December 2020

Alternate-day fasting and chronic disease prevention: a review of human and animal trials

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12 December 2020

Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein

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12 December 2020

Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system.

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12 December 2020

Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source

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12 December 2020

N-Acetylcysteine delays age-associated memory impairment in mice: role in synaptic mitochondria.

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12 December 2020

Disruption of estrogen receptor beta gene impairs spatial learning in female mice

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12 December 2020

Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease

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12 December 2020

Spontaneous spongy degeneration of the brain stem in SAM-P/8 mice, a newly developed memory-deficient strain.

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12 December 2020

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

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12 December 2020

10.1007/S11064-009-9923-X

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19247832