Interleukin-6 and insulin resistance (Q37403996)

20 August 2017

1 reference

title

Interleukin-6 and insulin resistance (English)

1 reference

20 August 2017

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1 reference

1 reference

Jeong-Ho Kim

1

1 reference

PubMed ID

19251052

20 August 2017

Rebecca A Bachmann

series ordinal

2

1 reference

PubMed ID

19251052

20 August 2017

Jie Chen

series ordinal

3

1 reference

20 August 2017

1 January 2009

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20 August 2017

Vitamins and Hormones

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20 August 2017

80

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20 August 2017

613-633

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

20 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

IKK-beta links inflammation to obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Snapin interacts with the Exo70 subunit of the exocyst and modulates GLUT4 trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Elevated Levels of Interleukin 6 Are Reduced in Serum and Subcutaneous Adipose Tissue of Obese Women after Weight Loss

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Metabolic syndrome: from global epidemiology to individualized medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The role of SOCS-3 in leptin signaling and leptin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin signal transduction in human skeletal muscle: identifying the defects in Type II diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

STAT proteins: From normal control of cellular events to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 and insulin sensitivity: friend or foe?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

SOCS3 negatively regulates IL-6 signaling in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

SOCS-3 is an insulin-induced negative regulator of insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Reduced exercise endurance in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin resistance-inducing cytokines differentially regulate SOCS mRNA expression via growth factor- and Jak/Stat-signaling pathways in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The endothelium and vascular inflammation in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

A central role for JNK in obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Mechanisms of TNF-alpha-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Attenuation of leptin and insulin signaling by SOCS proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Inflammatory markers and risk of developing type 2 diabetes in women.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The GLUT4 glucose transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 production by contracting human skeletal muscle: autocrine regulation by IL-6

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Advanced oxidation protein products in obese women: its relation to insulin resistance and resistin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Impact of Weight Loss on Inflammatory Proteins and Their Association With the Insulin Resistance Syndrome in Morbidly Obese Patients

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

A new role for SOCS in insulin action. Suppressor of cytokine signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Serine phosphorylation and negative regulation of Stat3 by JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Regulation of Stat3 activation by MEK kinase 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Regulation of gene expression by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 induces cellular insulin resistance in hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Nitric oxide production is a proximal signaling event controlling exercise-induced mRNA expression in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 enhances glucose transport in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

The dual function of hepatic SOCS3 in insulin resistance in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Glucose transport into rat skeletal muscle: interaction between exercise and insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

IRS proteins and the common path to diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Insulin signaling in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

Interleukin-6 in biology and medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900621-3

7 January 2021

10.1016/S0083-6729(08)00621-3

Identifiers

DOI

1 reference

20 August 2017

1 reference

PubMed ID

19251052