A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents (Q37410202)

20 August 2017

A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents (English)

1 reference

20 August 2017

arterial hypertension

0 references

pulmonary hypertension

1 reference

inferred from title

author

Marie-Camille Chaumais

Marie-Camille Chaumais

5

0 references

Ly Tu

Ly Tu

1

0 references

Alice Huertas

Alice Huertas

4

0 references

Peter Dorfmuller

Peter Dorfmüller

9

0 references

Frédéric Perros

Frédéric Perros

8

0 references

Christophe Guignabert

Christophe Guignabert

14

0 references

David Montani

David Montani

11

0 references

Marc Humbert

Marc Humbert

13

0 references

Florence Lecerf

6

Florence Lecerf

1 reference

20 August 2017

3

Barbara Girerd

1 reference

20 August 2017

10

Elie Fadel

1 reference

20 August 2017

12

Saadia Eddahibi

1 reference

20 August 2017

Frances S De Man

2

1 reference

PMCID

5106524

20 August 2017

Charlène François

7

1 reference

PMCID

5106524

20 August 2017

language of work or name

English

0 references

publication date

12 July 2012

1 reference

American Journal of Respiratory and Critical Care Medicine

20 August 2017

1 reference

20 August 2017

186

1 reference

20 August 2017

7

1 reference

20 August 2017

666-676

1 reference

FGFR3 is overexpressed waldenstrom macroglobulinemia and its inhibition by Dovitinib induces apoptosis and overcomes stroma-induced proliferation

20 August 2017

1 reference

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Role for miR-204 in human pulmonary arterial hypertension

9 September 2017

1 reference

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9 September 2017

1 reference

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Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension

9 September 2017

1 reference

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Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy.

9 September 2017

1 reference

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p130Cas is an essential transducer element in ErbB2 transformation

9 September 2017

1 reference

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p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.

9 September 2017

1 reference

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Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.

9 September 2017

1 reference

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9 September 2017

1 reference

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Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents

9 September 2017

1 reference

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Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

9 September 2017

1 reference

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9 September 2017

1 reference

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9 September 2017

1 reference

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Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension

9 September 2017

1 reference

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The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling

9 September 2017

1 reference

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Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

9 September 2017

1 reference

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p130Cas: a versatile scaffold in signaling networks

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Reversal of experimental pulmonary hypertension by PDGF inhibition

9 September 2017

1 reference

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Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

9 September 2017

1 reference

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Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

PDGF and cardiovascular disease

9 September 2017

1 reference

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Signal transduction and oncogenesis by ErbB/HER receptors

9 September 2017

1 reference

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Current targets for anticancer drug discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

The prognostic value of BCAR1 in patients with primary breast cancer.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

The cancer paradigm of severe pulmonary arterial hypertension

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22alpha-targeted overexpression of the serotonin transporter.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Circulating endothelial microparticle levels predict hemodynamic severity of pulmonary hypertension

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Expression of FGF-2 alters focal adhesion dynamics in migration-restricted MDA-MB-231 breast cancer cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5106524

BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1164%2FRCCM.201202-0309OC

Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1164%2FRCCM.201202-0309OC

cSrc is a major cytosolic tyrosine kinase in vascular tissue

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22798315

12 December 2020

inferred from PubMed ID database lookup

Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22798315

12 December 2020

inferred from PubMed ID database lookup

Breast cancer anti-estrogen resistance protein 1 (BCAR1/p130cas) in pulmonary disease tissue and serum

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22798315

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1164/RCCM.201202-0309OC

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

5106524