Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study (Q37413059)

20 August 2017

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study (English)

1 reference

20 August 2017

0 references

James H McMahon

2

0 references

Sharon R. Lewin

object named as

Sharon R Lewin

16

0 references

Steven G Deeks

15

object named as

Steven G Deeks

1 reference

20 August 2017

12

Robert J Gorelick

1 reference

20 August 2017

6

Namandje Bumpus

1 reference

20 August 2017

Julian H Elliott

1

1 reference

20 August 2017

Christina C Chang

3

1 reference

20 August 2017

Sulggi A Lee

4

1 reference

20 August 2017

Wendy Hartogensis

5

1 reference

20 August 2017

Rada Savic

7

1 reference

20 August 2017

Janine Roney

8

1 reference

20 August 2017

Rebecca Hoh

9

1 reference

20 August 2017

Ajantha Solomon

10

1 reference

20 August 2017

Michael Piatak

11

1 reference

20 August 2017

Jeff Lifson

13

1 reference

20 August 2017

Peter Bacchetti

14

1 reference

20 August 2017

17 November 2015

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20 August 2017

1 reference

20 August 2017

2

1 reference

20 August 2017

12

1 reference

20 August 2017

e520-9

1 reference

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

HIV infection: epidemiology, pathogenesis, treatment, and prevention

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Circadian regulator CLOCK is a histone acetyltransferase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Decay characteristics of HIV-1-infected compartments during combination therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Elimination kinetics of disulfiram in alcoholics after single and repeated doses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Disulfiram therapy--adverse drug reactions and interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Hydrocortisone and some other hormones enhance the expression of HTLV-III.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Diurnal rhythms in blood cell populations and the effect of acute sleep deprivation in healthy young men.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Norepinephrine accelerates HIV replication via protein kinase A-dependent effects on cytokine production

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Kinetics of HIV-1 RNA concentration changes in pediatric patients

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5108570

Side effects after disulfiram. Comparison of disulfiram and placebo in a double-blind multicentre study

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS2352-3018%2815%2900226-X

inferred from DOI database lookup

7 January 2021

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/26614966

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S2352-3018(15)00226-X

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

26614966

1 reference