Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine. (Q37413548)

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10 February 2020

title

Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine (English)

1 reference

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10 February 2020

1 reference

1

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10 February 2020

Robert T Sauer

series ordinal

2

1 reference

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10 February 2020

author name string

Eyal Gur

series ordinal

1

1 reference

20 August 2017

Robert T Sauer

series ordinal

2

1 reference

20 August 2017

language of work or name

English

0 references

publication date

19 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19841274%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

10 February 2020

published in

1 reference

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10 February 2020

volume

106

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10 February 2020

issue

44

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10 February 2020

page(s)

18503-18508

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Evolution of the ssrA degradation tag in Mycoplasma: specificity switch to a different protease

10 February 2020

cites work

1 reference

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Recognition of misfolded proteins by Lon, a AAA(+) protease

6 September 2017

1 reference

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Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging.

6 September 2017

1 reference

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Lon protease degrades transfer-messenger RNA-tagged proteins

6 September 2017

1 reference

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ATP-dependent proteases of bacteria: recognition logic and operating principles

6 September 2017

1 reference

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Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains

6 September 2017

1 reference

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Biological roles of the Lon ATP-dependent protease

6 September 2017

1 reference

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Sequence requirements for Lon-dependent degradation of the Escherichia coli transcription activator SoxS: identification of the SoxS residues critical to proteolysis and specific inhibition of in vitro degradation by a peptide comprised of the N-ter

6 September 2017

1 reference

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Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing

6 September 2017

1 reference

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Sculpting the proteome with AAA(+) proteases and disassembly machines.

6 September 2017

1 reference

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

6 September 2017

1 reference

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Regulation of SulA cleavage by Lon protease by the C-terminal amino acid of SulA, histidine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Substrate sequestration by a proteolytically inactive Lon mutant

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Lon-mediated proteolysis of the Escherichia coli UmuD mutagenesis protein: in vitro degradation and identification of residues required for proteolysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

The product of the lon (capR) gene in Escherichia coli is the ATP-dependent protease, protease La.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Degradation of abnormal proteins in Escherichia coli (protein breakdown-protein structure-mistranslation-amino acid analogs-puromycin).

6 September 2017

1 reference

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Proteases and their targets in Escherichia coli

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Detection and characterization of two ATP-dependent conformational changes in proteolytically inactive Escherichia coli Lon mutants by stopped flow kinetic techniques

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation

2 September 2018

1 reference

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Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Kinetic characterization of the peptidase activity of Escherichia coli Lon reveals the mechanistic similarities in ATP-dependent hydrolysis of peptide and protein substrates

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Functional role of the N-terminal region of the Lon protease from Mycobacterium smegmatis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774003

Identification and transcriptional organization of aerobactin transport and biosynthesis cluster genes of Vibrio hollisae

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0910392106

Coupled assay of Na+,K+-ATPase activity

21 January 2018

1 reference

12 December 2020

Selectivity of intracellular proteolysis: protein substrates activate the ATP-dependent protease (La)

1 reference

12 December 2020

PinA inhibits ATP hydrolysis and energy-dependent protein degradation by Lon protease

1 reference

12 December 2020

Regulatory role of C-terminal residues of SulA in its degradation by Lon protease in Escherichia coli

1 reference

12 December 2020

Purification and allosteric properties of a nicotinamide adenine dinucleotide-linked D(-)-specific lactate dehydrogenase from Butyribacterium rettgeri

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0910392106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19841274%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19841274%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

19841274

1 reference