Substrate specificity of purified recombinant human β-carotene 15,15'-oxygenase (BCO1) (Q37415646)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24187135%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Substrate specificity of purified recombinant human β-carotene 15,15'-oxygenase (BCO1) (English)

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29 February 2020

3

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29 February 2020

Steven J. Schwartz

5

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29 February 2020

author name string

Carlo dela Seña

1

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29 February 2020

Sureshbabu Narayanasamy

2

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29 February 2020

Robert W Curley

4

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29 February 2020

Earl H Harrison

6

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29 February 2020

language of work or name

English

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publication date

1 November 2013

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Journal of Biological Chemistry

29 February 2020

published in

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29 February 2020

volume

288

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issue

52

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29 February 2020

page(s)

37094-37103

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Naturally occurring eccentric cleavage products of provitamin A β-carotene function as antagonists of retinoic acid receptors

29 February 2020

cites work

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Analysis, occurrence, and function of 9-cis-retinoic acid

6 September 2017

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Dietary 9-cis-β,β-carotene fails to rescue vision in mouse models of leber congenital amaurosis

6 September 2017

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Carotene and novel apocarotenoid concentrations in orange-fleshed Cucumis melo melons: determinations of β-carotene bioaccessibility and bioavailability

6 September 2017

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6 September 2017

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The structure of a retinal-forming carotenoid oxygenase

6 September 2017

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Provitamin A conversion to retinal via the beta,beta-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis

6 September 2017

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Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids

6 September 2017

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Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium

6 September 2017

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Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

6 September 2017

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Cloning and expression of beta,beta-carotene 15,15'-dioxygenase

6 September 2017

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Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

6 September 2017

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Stimulation of gap junctional communication: comparison of acyclo-retinoic acid and lycopene

6 September 2017

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Dietary carotenoids and their role in combating vitamin A deficiency: a review of the literature.

6 September 2017

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Evidence of cis-trans isomerization of 9-cis-beta-carotene during absorption in humans

6 September 2017

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The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine

6 September 2017

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9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

6 September 2017

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9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

6 September 2017

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Utilization of the recombinant human beta-carotene-15,15'-monooxygenase gene in Escherichia coli and mammalian cells

6 September 2017

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Biological activity of (all-E)-beta-apo-12'-carotenoic acid and the geometrical isomers on human acute promyelocytic leukemia cell line HL-60.

14 September 2017

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Asymmetric cleavage of beta-carotene yields a transcriptional repressor of retinoid X receptor and peroxisome proliferator-activated receptor responses

28 September 2017

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Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase

26 June 2018

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Assay of beta-carotene 15,15'-dioxygenase activity by reverse-phase high-pressure liquid chromatography

26 June 2018

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Human serum concentrations of all-trans beta- and alpha-carotene but not 9-cis beta-carotene increase upon ingestion of a natural isomer mixture obtained from Dunaliella salina (Betatene).

26 June 2018

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Isomerization of all-trans-retinoic acid to 9-cis-retinoic acid

26 June 2018

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Purification and properties of carotene 15,15'-dioxygenase of rabbit intestine

26 June 2018

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Characterization of beta-apo-13-carotenone and beta-apo-14'-carotenal as enzymatic products of the excentric cleavage of beta-carotene

26 June 2018

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The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα.

26 June 2018

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Substrate specificity of a recombinant chicken beta-carotene 15,15'-monooxygenase that converts beta-carotene into retinal

2 September 2018

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Excentral cleavage of beta-carotene in vivo in a healthy man.

2 September 2018

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Development of a versatile reporter assay for studies of retinol uptake and metabolism in vivo

2 September 2018

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Excentric cleavage products of beta-carotene inhibit estrogen receptor positive and negative breast tumor cell growth in vitro and inhibit activator protein-1-mediated transcriptional activation

2 September 2018

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Acyclo-retinoic acid induces apoptosis in human prostate cancer cells

2 September 2018

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Effects of acyclo-retinoic acid and lycopene on activation of the retinoic acid receptor and proliferation of mammary cancer cells.

2 September 2018

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Quantification of the "SLAMENGHI" factors for carotenoid bioavailability and bioconversion.

2 September 2018

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Identification, quantification, and relative concentrations of carotenoids and their metabolites in human milk and serum.

2 September 2018

1 reference

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Vitamin A and carotenoids. The enzymic conversion of β-carotene into retinal in hog intestinal mucosa

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3873565

The effect of alpha-tocopherol on the oxidative cleavage of beta-carotene

2 September 2018

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12 December 2020

The specificity of a partially purified carotenoid cleavage enzyme of rabbit intestine

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12 December 2020

Retinal is not formed in vitro by enzymatic central cleavage of beta-carotene

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12 December 2020

Structural and geometrical isomers of carotenoids in human plasma

1 reference

12 December 2020

Enzymatic conversion of beta-carotene into beta-apo-carotenals and retinoids by human, monkey, ferret, and rat tissues

1 reference

12 December 2020

Biosynthesis of 9-cis-retinoic acid from 9-cis-beta-carotene in human intestinal mucosa in vitro

1 reference

12 December 2020

Thiol dependent isomerization of all-trans-retinoic acid to 9-cis-retinoic acid

1 reference

12 December 2020

Enzymatic formation of 9-cis, 13-cis, and all-trans retinals from isomers of beta-carotene

1 reference

12 December 2020

beta-Carotene-15,15'-dioxygenase (EC 1.13.11.21) isolation reaction mechanism and an improved assay procedure

1 reference

12 December 2020

Detection of bixin, lycopene, canthaxanthin, and beta-apo-8'-carotenal in products derived from red pepper

1 reference

12 December 2020

Discrimination in absorption or transport of beta-carotene isomers after oral supplementation with either all-trans- or 9-cis-beta-carotene

1 reference

12 December 2020

Lutein, lycopene, and their oxidative metabolites in chemoprevention of cancer

1 reference

12 December 2020

Bioavailability of a natural isomer mixture compared with synthetic all-trans beta-carotene in human serum

1 reference

12 December 2020

In vitro and in vivo inhibition of beta-carotene dioxygenase activity by canthaxanthin in rat intestine

1 reference

12 December 2020

BIOSYNTHESIS OF VITAMIN A WITH RAT INTESTINAL ENZYMES

1 reference

12 December 2020

Apo-8'-lycopenal and apo-12'-lycopenal are metabolic products of lycopene in rat liver

1 reference

12 December 2020

Lycopene isomerisation takes place within enterocytes during absorption in human subjects

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12 December 2020

Identifiers

DOI

10.1074/JBC.M113.507160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24187135%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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29 February 2020

PubMed publication ID

24187135

1 reference