Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. (Q37420333)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24253446%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases (English)

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1 March 2020

0 references

1 reference

1

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1 March 2020

Sangsu Bae

6

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1 March 2020

author name string

Sojung Kim

2

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1 March 2020

Yongsub Kim

3

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1 March 2020

Jiyeon Kweon

4

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1 March 2020

Heon Seok Kim

5

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1 March 2020

Jin-Soo Kim

7

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1 March 2020

publication date

19 November 2013

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1 March 2020

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1 March 2020

volume

24

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1 March 2020

issue

1

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1 March 2020

page(s)

132-141

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

1 March 2020

cites work

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

23 August 2017

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

23 August 2017

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DNA targeting specificity of RNA-guided Cas9 nucleases

23 August 2017

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

23 August 2017

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Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

23 August 2017

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Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease.

23 August 2017

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

23 August 2017

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Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

23 August 2017

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Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos

23 August 2017

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A library of TAL effector nucleases spanning the human genome

23 August 2017

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RNA-programmed genome editing in human cells

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

23 August 2017

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

23 August 2017

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Efficient genome editing in zebrafish using a CRISPR-Cas system

23 August 2017

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RNA-guided human genome engineering via Cas9

23 August 2017

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Multiplex genome engineering using CRISPR/Cas systems

23 August 2017

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Efficient TALEN-mediated gene knockout in livestock

23 August 2017

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

23 August 2017

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Precision genome engineering with programmable DNA-nicking enzymes

23 August 2017

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FLASH assembly of TALENs for high-throughput genome editing

23 August 2017

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Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

23 August 2017

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Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

23 August 2017

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RNA-guided genetic silencing systems in bacteria and archaea

23 August 2017

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Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

23 August 2017

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Detection of structural variants and indels within exome data

23 August 2017

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Performance comparison of exome DNA sequencing technologies

23 August 2017

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

23 August 2017

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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

23 August 2017

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23 August 2017

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Targeted chromosomal deletions in human cells using zinc finger nucleases

23 August 2017

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Breaking the code of DNA binding specificity of TAL-type III effectors

23 August 2017

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Chromosomal translocations induced at specified loci in human stem cells.

23 August 2017

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Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

23 August 2017

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Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

23 August 2017

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Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

23 August 2017

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An improved zinc-finger nuclease architecture for highly specific genome editing

23 August 2017

1 reference

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Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

23 August 2017

1 reference

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875854

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875854

Human zinc fingers as building blocks in the construction of artificial transcription factors.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875854

An unbiased genome-wide analysis of zinc-finger nuclease specificity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875854

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3875854

TALENs and ZFNs are associated with different mutation signatures

2 September 2018

1 reference

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Knockout mice created by TALEN-mediated gene targeting

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24253446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Preassembled zinc-finger arrays for rapid construction of ZFNs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24253446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GR.162339.113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24253446%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24253446%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24253446%20AND%20SRC:MED&resulttype=core&format=json