Covalent small-molecule-RNA complex formation enables cellular profiling of small-molecule-RNA interactions (Q37421427)

20 August 2017

Covalent small-molecule-RNA complex formation enables cellular profiling of small-molecule-RNA interactions (English)

1 reference

20 August 2017

Lirui Guan

1

1 reference

PMCID

3876275

20 August 2017

Matthew D Disney

series ordinal

2

1 reference

PMCID

3876275

20 August 2017

language of work or name

English

0 references

publication date

1 August 2013

1 reference

Angewandte Chemie International Edition

20 August 2017

0 references

volume

52

1 reference

20 August 2017

38

1 reference

20 August 2017

10010-10013

1 reference

Small-molecule-mediated cleavage of RNA in living cells

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

RNA splicing is responsive to MBNL1 dose

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Recent advances in developing small molecules targeting RNA.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Autoregulated splicing of muscleblind-like 1 (MBNL1) Pre-mRNA.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Pentamidine reverses the splicing defects associated with myotonic dystrophy.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

A small molecule microarray platform to select RNA internal loop-ligand interactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

The bacterial ribosome as a target for antibiotics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Pre-mRNA splicing and human disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Mechanisms of in situ activation for DNA-targeting antitumor agents

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Factors influencing the extent and selectivity of alkylation within triplexes by reactive G/A motif oligonucleotides

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

RNA-Pt adducts following cisplatin treatment of Saccharomyces cerevisiae

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Chlorambucil-adducts in DNA analyzed at the oligonucleotide level using HPLC-ESI MS.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

A new role for cisplatin: probing ribosomal RNA structure

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3876275

Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201301639

Alkylation of guanosine by phosphoramide mustard, chloromethine hydrochloride and chlorambucil

21 January 2018

1 reference

12 December 2020

Chlorambucil in treatment of chronic lymphocytic leukemia and certain lymphomas

1 reference

12 December 2020

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

1 reference

12 December 2020

Targeting RNA with small molecules

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANIE.201301639

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

3876275