Polyamines: from molecular biology to clinical applications (Q37421694)

20 August 2017

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title

Polyamines: from molecular biology to clinical applications (English)

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20 August 2017

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Jänne J

1

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20 August 2017

Alhonen L

series ordinal

2

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20 August 2017

Leinonen P

series ordinal

3

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20 August 2017

language of work or name

English

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publication date

1 August 1991

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20 August 2017

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20 August 2017

23

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20 August 2017

3

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20 August 2017

241-259

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Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors

20 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Biosynthesis of putrescine in the prostate gland of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Molecular cloning and expression of the mouse ornithine decarboxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Androgen induction of ornithine decarboxylase mRNA in mouse kidney as studied by complementary DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Isolation of cloned cDNA encoding mammalian ornithine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Recent advances in the biochemistry of polyamines in eukaryotes

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853899109148056

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Nucleotide sequence of the mouse ornithine decarboxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Nucleotide sequence of the 5'-flanking region of the murine ornithine decarboxylase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Cloning and functional analysis of the rat ornithine decarboxylase-encoding gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Nucleotide sequence of the human ornithine decarboxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Characterization and sequence analysis of the human ornithine decarboxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Human ornithine decarboxylase-encoding loci: nucleotide sequence of the expressed gene and characterization of a pseudogene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Human ornithine decarboxylase sequences map to chromosome regions 2pter----p23 and 7cen----qter but are not coamplified with the NMYC oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

A functional mouse ornithine decarboxylase gene (Odc) maps to chromosome 12: further evidence of homoeology between mouse chromosome 12 and the short arm of human chromosome 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Evidence for the presence of pyruvate in rat liverS-adenosylmethionine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Monospecific antiserum to rat spermidine synthase and its application to rat tissues and several mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Human spermidine synthase: cloning and primary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Cadaverine and putrescine initiate the burial of dead conspecifics by rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Translational regulation of ornithine decarboxylase by polyamines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Control of enzyme levels in animal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

1,4-Diaminobutane (putrescine), spermidine, and spermine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Overproduction of ornithine decarboxylase confers an apparent growth advantage to mouse tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

The significance of DNA methylation patterns: promoter inhibition by sequence-specific methylation is one functional consequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Cytosine methylation in CTF and Sp1 recognition sites of an HSV tk promoter: effects on transcription in vivo and on factor binding in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Eukaryotic DNA methylation: facts and problems

21 January 2018

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https://api.crossref.org/works/10.3109%2F07853899109148056

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Specific protection of methylated CpGs in mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Chronic exposure to dexamethasone induces hypomethylation of ornithine decarboxylase genes in a human myeloma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Stimulation of the decarboxylation of S-adenosylmethionine by putrescine in mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Polyamines are needed for the differentiation of 3T3-L1 fibroblasts into adipose cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Regulation of ornithine decarboxylase activity by spermidine and the spermidine analogue N1N8-bis(ethyl)spermidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Enzyme regulation as an approach to interference with polyamine biosynthesis--an alternative to enzyme inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Difluoromethylornithine-induced amplification of ornithine decarboxylase genes in Ehrlich ascites carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Cadaverine supplementation during a chronic exposure to difluoromethylornithine allows an overexpression, but prevents gene amplification, of ornithine decarboxylase in L1210 mouse leukaemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

S-adenosylmethionine decarboxylase as target of chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-l-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Effects of bis(guanylhydrazones) on the activity and expression of ornithine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Inhibition of diamine oxidase by 1,1-[(methylethanediylidene)-dinitrilo]-bis-(3-aminoguanidine) and 1,1'-[(methylethanediylidene)-dinitrilo]-diguanidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Quantitation of methylglyoxal bis(guanylhydrazone) in blood plasma and leukemia cells of patients receiving the drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Methylglyoxal bis(butylamidinohydrazone), a new inhibitor of polyamine biosynthesis that simultaneously inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Antitumor effect of methylglyoxal bis(butylamidinohydrazone), a new inhibitor of S-adenosylmethionine decarboxylase, against human erythroid leukemia K 562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Inhibition of mouse skin tumor promotion and of promoter-induced epidermal polyamine biosynthesis by methylglyoxal bis(butylamidinohydrazone).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Growth of mammalian cells in the absence of the accumulation of spermine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Effects of S-adenosyl-1,8-diamino-3-thiooctane on polyamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Antigrowth effect of polyamine biosynthesis inhibitors on the Dunning R 3327-G prostatic tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Intestinal changes caused by DL-alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Cochlear damage and increased threshold in alpha-difluoromethylornithine (DFMO) treated guinea pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Radiosensitization of human tumor cells by alpha-difluoromethylornithine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Difluoromethylornithine enhances inhibition of melanoma cell growth in soft agar by dexamethasone, clone A interferon and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

A phase I study of hepatic arterial infusion using difluoromethylornithine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Phase I study of alpha-difluoromethylornithine and methyl-GAG.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

New therapeutic approaches for brain tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Difluoromethylornithine and leukocyte interferon: a phase I study in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

MIME chemotherapy (methyl-GAG, ifosfamide, methotrexate, etoposide) as treatment for recurrent Hodgkin's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Ultraviolet light induces epidermal ornithine decarboxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Effects of ultraviolet light on epidermal polyamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Polyamine inhibitors in antimicrobial chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Antagonism by polyamines of the curative effects of alpha-difluoromethylornithine in Trypanosoma brucei brucei infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Novel combination chemotherapy of experimental trypanosomiasis by using bleomycin and DL-α-difluoromethylornithine; reversal by polyamines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Chemotherapeutic implications of polyamine biosynthesis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Difiuoromethylornithine in the treatment of African trypanosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899109148056

10.3109/07853899109148056

21 January 2018

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DOI

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20 August 2017

1 reference